Skeletal disorders associated with the growth hormone–insulin-like growth factor 1 axis

G Mazziotti, AG Lania, E Canalis - Nature Reviews Endocrinology, 2022 - nature.com
Growth hormone (GH) and insulin-like growth factor 1 (IGF1) are important regulators of
bone remodelling and metabolism and have an essential role in the achievement and …

The role of adiponectin in cancer: a review of current evidence

M Dalamaga, KN Diakopoulos… - Endocrine …, 2012 - academic.oup.com
Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline

ME Molitch, DR Clemmons… - The Journal of …, 2011 - academic.oup.com
Objective: The aim was to update The Endocrine Society Clinical Practice Guideline on
Evaluation and Treatment of Adult Growth Hormone Deficiency (GHD) previously published …

Growth hormone, insulin-like growth factors, and the skeleton

A Giustina, G Mazziotti, E Canalis - Endocrine reviews, 2008 - academic.oup.com
Abstract GH and IGF-I are important regulators of bone homeostasis and are central to the
achievement of normal longitudinal bone growth and bone mass. Although GH may act …

Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society Clinical Practice Guideline

ME Molitch, DR Clemmons… - The Journal of …, 2006 - academic.oup.com
Objective: The objective is to provide guidelines for the evaluation and treatment of adults
with GH deficiency (GHD). Participants: The chair of the Task Force was selected by the …

Pituitary diseases and bone

G Mazziotti, S Frara, A Giustina - Endocrine reviews, 2018 - academic.oup.com
Neuroendocrinology of bone is a new area of research based on the evidence that pituitary
hormones may directly modulate bone remodeling and metabolism. Skeletal fragility …

Treatment with growth hormone for adults with growth hormone deficiency syndrome: benefits and risks

JJ Díez, S Sangiao-Alvarellos, F Cordido - International journal of …, 2018 - mdpi.com
Pharmacological treatment of growth hormone deficiency (GHD) in adults began in clinical
practice more than 20 years ago. Since then, a great volume of experience has been …

[HTML][HTML] Hormone replacement therapy and physical function in healthy older men. Time to talk hormones?

MG Giannoulis, FC Martin, KS Nair… - Endocrine …, 2012 - ncbi.nlm.nih.gov
Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Effects of growth hormone on bone

NA Tritos, A Klibanski - Progress in molecular biology and translational …, 2016 - Elsevier
Purpose Describe the effects of growth hormone (GH) and insulin-like growth factor 1 (IGF-1)
on the skeleton. Findings The GH and IGF-1 axis has pleiotropic effects on the skeleton …

Diagnosis and treatment of growth hormone deficiency in adults

AY Kargi, GR Merriam - Nature Reviews Endocrinology, 2013 - nature.com
The availability of synthetic recombinant human growth hormone (GH) in potentially
unlimited quantities since the 1980s has improved understanding of the many nonstatural …