Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding

US Tantry, L Bonello, D Aradi, MJ Price… - Journal of the American …, 2013 - jacc.org
Dual antiplatelet therapy with aspirin and a P2Y12 receptor blocker is a key strategy to
reduce platelet reactivity and to prevent thrombotic events in patients treated with …

Bleeding and stent thrombosis on P2Y12-inhibitors: collaborative analysis on the role of platelet reactivity for risk stratification after percutaneous coronary …

D Aradi, A Kirtane, L Bonello, PA Gurbel… - European heart …, 2015 - academic.oup.com
Aims Although platelet reactivity during P2Y12-inhibitors is associated with stent thrombosis
(ST) and bleeding, standardized and clinically validated thresholds for accurate risk …

Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study

GW Stone, B Witzenbichler, G Weisz, MJ Rinaldi… - The Lancet, 2013 - thelancet.com
Background The relation between platelet reactivity and stent thrombosis, major bleeding,
and other adverse events after coronary artery implantation of drug-eluting stents has been …

Pharmacology of antithrombotic drugs: an assessment of oral antiplatelet and anticoagulant treatments

JL Mega, T Simon - The Lancet, 2015 - thelancet.com
Antithrombotic drugs, which include antiplatelet and anticoagulant therapies, prevent and
treat many cardiovascular disorders and, as such, are some of the most commonly …

The low dose colchicine after myocardial infarction (LoDoCo-MI) study: a pilot randomized placebo controlled trial of colchicine following acute myocardial infarction

T Hennessy, L Soh, M Bowman, R Kurup, C Schultz… - American heart …, 2019 - Elsevier
Background Following an acute myocardial infarction (MI), patients with persistently
elevated biomarkers of inflammation, in particular C-reactive protein (CRP), are at …

[HTML][HTML] Relationship between post‐treatment platelet reactivity and ischemic and bleeding events at 1‐year follow‐up in patients receiving prasugrel

L Bonello, J Mancini, M Pansieri, L Maillard… - Journal of Thrombosis …, 2012 - Elsevier
Background: Post‐treatment platelet reactivity (PR) is associated with ischemic and bleeding
events in patients receiving P2Y12 receptor antagonists. Objectives: We aimed to study the …

Invasive assessment of coronary microvascular function

F Mangiacapra, MM Viscusi, G Verolino… - Journal of Clinical …, 2021 - mdpi.com
The critical role of the coronary microvascular compartment and its invasive functional
assessment has become apparent in light of the significant proportion of patients presenting …

Platelet function tests in clinical cardiology: unfulfilled expectations

DA Gorog, V Fuster - Journal of the American College of Cardiology, 2013 - jacc.org
This review is a critical evaluation of publications in the past decade on the usefulness of
platelet function tests (PFTs) in clinical cardiology, in aiding diagnosis, predicting risk, and …

Precision medicine to improve use of bleeding avoidance strategies and reduce bleeding in patients undergoing percutaneous coronary intervention: prospective …

JA Spertus, C Decker, E Gialde, PG Jones, EJ McNulty… - bmj, 2015 - bmj.com
Objective To examine whether prospective bleeding risk estimates for patients undergoing
percutaneous coronary intervention could improve the use of bleeding avoidance strategies …

[HTML][HTML] Optimal cutoff value of P2Y12 reaction units to prevent major adverse cardiovascular events in the acute periprocedural period: post-hoc analysis of the …

M Nakamura, T Isshiki, T Kimura, H Ogawa… - International Journal of …, 2015 - Elsevier
Background Few studies have examined the effects of on-treatment platelet reactivity on the
risk of major adverse cardiovascular events (MACE). We aimed to determine the optimal …