Nonlinear decision-making with enzymatic neural networks

S Okumura, G Gines, N Lobato-Dauzier, A Baccouche… - Nature, 2022 - nature.com
Artificial neural networks have revolutionized electronic computing. Similarly, molecular
networks with neuromorphic architectures may enable molecular decision-making on a level …

Reservoir computing using DNA oscillators

X Liu, KK Parhi - ACS Synthetic Biology, 2022 - ACS Publications
This paper presents novel implementations for reservoir computing (RC) using DNA
oscillators. An RC system consists of two parts: reservoir and readout layer. The reservoir …

On reaction network implementations of neural networks

DF Anderson, B Joshi… - Journal of the Royal …, 2021 - royalsocietypublishing.org
This paper is concerned with the utilization of deterministically modelled chemical reaction
networks for the implementation of (feed-forward) neural networks. We develop a general …

A loser-take-all DNA circuit

KR Rodriguez, N Sarraf, L Qian - ACS Synthetic Biology, 2021 - ACS Publications
DNA-based neural networks are a type of DNA circuit capable of molecular pattern
recognition tasks. Winner-take-all DNA networks have been developed to scale up the …

A cooperative DNA catalyst

DN Taylor, SR Davidson, L Qian - Journal of the American …, 2021 - ACS Publications
DNA catalysts are fundamental building blocks for diverse molecular information-processing
circuits. Allosteric control of DNA catalysts has been developed to activate desired catalytic …

Design and simulation of a multilayer chemical neural network that learns via backpropagation

MR Lakin - Artificial Life, 2023 - direct.mit.edu
The design and implementation of adaptive chemical reaction networks, capable of
adjusting their behavior over time in response to experience, is a key goal for the fields of …

[HTML][HTML] Synthetic biological neural networks: From current implementations to future perspectives

AH Vasle, M Moškon - Biosystems, 2024 - Elsevier
Artificial neural networks, inspired by the biological networks of the human brain, have
become game-changing computing models in modern computer science. Inspired by their …

Programming and training rate-independent chemical reaction networks

M Vasić, C Chalk, A Luchsinger… - Proceedings of the …, 2022 - National Acad Sciences
Embedding computation in biochemical environments incompatible with traditional
electronics is expected to have a wide-ranging impact in synthetic biology, medicine …

Automatic Implementation of Neural Networks through Reaction Networks--Part I: Circuit Design and Convergence Analysis

Y Fan, X Zhang, C Gao, D Dochain - arXiv preprint arXiv:2311.18313, 2023 - arxiv.org
Information processing relying on biochemical interactions in the cellular environment is
essential for biological organisms. The implementation of molecular computational systems …

CRNs exposed: Systematic exploration of chemical reaction networks

M Vasic, D Soloveichik, S Khurshid - arXiv preprint arXiv:1912.06197, 2019 - arxiv.org
Formal methods have enabled breakthroughs in many fields, such as in hardware
verification, machine learning and biological systems. The key object of interest in systems …