Dry eye disease: identification and therapeutic strategies for primary care clinicians and clinical specialists

J Sheppard, B Shen Lee, LM Periman - Annals of medicine, 2023 - Taylor & Francis
Dry eye disease (DED) is a multifactorial disorder characterized by loss of tear film
homeostasis with an estimated worldwide prevalence of 5% to 50%. In DED, dysfunction of …

Ocular manifestations of rosacea: A clinical review

S Tavassoli, N Wong, E Chan - Clinical & experimental …, 2021 - Wiley Online Library
Ocular rosacea is a chronic inflammatory condition that can occur in the absence of
cutaneous features. The most common ocular features are chronic blepharoconjunctivitis …

[HTML][HTML] Emerging strategies for the diagnosis and treatment of meibomian gland dysfunction: proceedings of the OCEAN group meeting

G Geerling, C Baudouin, P Aragona, M Rolando… - The ocular …, 2017 - Elsevier
Meibomian gland dysfunction (MGD) is a common and chronic disorder that has a significant
adverse impact on patients' quality of life. It is a leading cause of evaporative dry eye …

Systemic conditions associated with severity of dry eye signs and symptoms in the dry eye assessment and management study

K Yu, V Bunya, M Maguire, P Asbell, GS Ying… - Ophthalmology, 2021 - Elsevier
Purpose Certain systemic conditions are reported to be risk factors for dry eye disease
(DED), but their associations with DED severity are not well studied. We evaluated whether …

S2k guideline: rosacea

BM Clanner‐Engelshofen, D Bernhard… - JDDG: Journal der …, 2022 - Wiley Online Library
This updated and upgraded S2k guideline deals with the diagnosis and treatment of
rosacea, which is a common, chronic inflammatory skin disease mostly affecting the face …

[HTML][HTML] Cutaneous and ocular rosacea: Common and specific physiopathogenic mechanisms and study models

D Rodrigues-Braz, M Zhao, N Yesilirmak… - Molecular …, 2021 - ncbi.nlm.nih.gov
Rosacea is a chronic inflammatory disease that affects the face skin. It is clinically classified
into the following four subgroups depending on its location and severity …

The growing need for validated biomarkers and endpoints for dry eye clinical research

NS Roy, Y Wei, E Kuklinski… - … ophthalmology & visual …, 2017 - iovs.arvojournals.org
Purpose: Biomarkers with minimally invasive and reproducible objective metrics provide the
key to future paradigm shifts in understanding of the underlying causes of dry eye disease …

Dry eye disease: emerging approaches to disease analysis and therapy

M Heidari, F Noorizadeh, K Wu, T Inomata… - Journal of clinical …, 2019 - mdpi.com
Dry eye disease (DED) is among the most common ocular disorders affecting tens of
millions of individuals worldwide; however, the condition remains incompletely understood …

[HTML][HTML] New insights into the morphology and function of meibomian glands

R Arita, S Fukuoka, N Morishige - Experimental eye research, 2017 - Elsevier
Meibomian glands secrete meibum, which gives rise to the lipid layer of the tear film and
thereby prevents excessive evaporation of tear fluid. Meibomian gland dysfunction (MGD) is …

Meibography: a Japanese perspective

R Arita - Investigative ophthalmology & visual science, 2018 - iovs.arvojournals.org
Meibography allows observation of meibomian glands in an objective and repeatable
manner. Original meibography systems were invasive and not readily adopted by …