Acute respiratory distress syndrome is a multifactorial lung injury that continues to be
associated with high levels of morbidity and mortality. Mechanical ventilation, although …

During the last decade, experimental and clinical studies have demonstrated that isolated
acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial organs and …

Purpose The optimal ventilatory settings in patients after cardiac arrest and their association
with outcome remain unclear. The aim of this study was to describe the ventilatory settings …

Over the last decade, the management of acute respiratory distress syndrome (ARDS) has
made considerable progress both regarding supportive and pharmacologic therapies. Lung …

Most patients with ischaemic stroke are managed on the ward or in specialty stroke units, but
a significant number requires higher-acuity care and, consequently, admission to the …

Background There is insufficient evidence to guide ventilatory targets in acute brain injury
(ABI). Recent studies have shown associations between mechanical power (MP) and …

Abstract Background Driving pressure (ΔP) and mechanical power (MP) are predictors of the
risk of ventilation-induced lung injuries (VILI) in mechanically ventilated patients …

Introduction Lung protective ventilation (LPV) comprising low tidal volume (VT) and high
positive end-expiratory pressure (PEEP) may compromise cerebral perfusion in acute brain …

Mechanical ventilation is a life-support system used to maintain adequate lung function in
patients who are critically ill or undergoing general anesthesia. The benefits and harms of …

Patients with traumatic brain injury (TBI) frequently require invasive mechanical ventilation
and admission to an intensive care unit. Ventilation of patients with TBI poses unique clinical …