Current classification, treatment options, and new perspectives in the management of adipocytic sarcomas

A De Vita, L Mercatali, F Recine, F Pieri… - OncoTargets and …, 2016 - Taylor & Francis
Sarcomas are a heterogeneous group of mesenchymal tumors arising from soft tissue or
bone, with an uncertain etiology and difficult classification. Soft tissue sarcomas (STSs) …

[HTML][HTML] Liposarcoma: advances in cellular and molecular genetics alterations and corresponding clinical treatment

L Yang, S Chen, P Luo, W Yan, C Wang - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Liposarcoma is a malignant tumor of mesenchymal origin with significant tissue diversity. It is
composed of adipocytes with different degrees of differentiation and different degrees of …

Cross‐flow microfiltration for isolation, selective capture and release of liposarcoma extracellular vesicles

L Casadei, A Choudhury, P Sarchet… - Journal of …, 2021 - Wiley Online Library
We present a resource‐efficient approach to fabricate and operate a micro‐nanofluidic
device that uses cross‐flow filtration to isolate and capture liposarcoma derived extracellular …

miR-135b, a key regulator of malignancy, is linked to poor prognosis in human myxoid liposarcoma

Y Nezu, K Hagiwara, Y Yamamoto, T Fujiwara… - Oncogene, 2016 - nature.com
Myxoid/round cell (RC) liposarcomas (MLS) were originally classified into two distinct
populations based on histological differences; a myxoid component and a RC component. It …

MDM2 Derived from Dedifferentiated Liposarcoma Extracellular Vesicles Induces MMP2 Production from Preadipocytes

L Casadei, F Calore, DA Braggio, A Zewdu… - Cancer research, 2019 - AACR
Dedifferentiated liposarcoma (DDLPS) is frequently diagnosed late, and patients typically
respond poorly to treatments. DDLPS is molecularly characterized by wild-type p53 and …

Diagnosis and treatment of myxoid liposarcomas: histology matters

S Abaricia, AC Hirbe - Current treatment options in oncology, 2018 - Springer
Opinion statement Sarcomas are a heterogeneous group of rare malignancies that arise
from mesenchymal cells and can occur anywhere in the body. Herein, the focus will be on …

Pharmacotherapy for liposarcoma: current state of the art and emerging systemic treatments

LP Suarez-Kelly, GG Baldi… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Liposarcomas are a heterogeneous group of soft tissue tumors that arise from
adipose tissue and are one of the most common soft tissue sarcomas found in adults …

G protein pathway suppressor 2 (GPS2) acts as a tumor suppressor in liposarcoma

XD Huang, FJ Xiao, SX Wang, RH Yin, CR Lu, QF Li… - Tumor Biology, 2016 - Springer
Liposarcoma (LPS) is the most common type of soft tissue sarcoma accounting for 20% of all
adult sarcomas. However, the molecular pathogenesis of this malignancy is still poorly …

[HTML][HTML] Prognostic model to predict survival outcome for curatively resected liposarcoma: a multi-institutional experience

YJ Oh, SY Yi, KH Kim, YJ Cho, SH Beum… - Journal of …, 2016 - ncbi.nlm.nih.gov
Purpose: We performed this study to analyze the clinical features and prognosis of Korean
patients with liposarcoma. Patients & Methods: Between October 1986 and April 2013, 231 …

Assessing the clinical value of microRNAs in formalin-fixed paraffin-embedded liposarcoma tissues: Overexpressed miR-155 is an indicator of poor prognosis

N Kapodistrias, K Mavridis, A Batistatou, P Gogou… - …, 2016 - pmc.ncbi.nlm.nih.gov
Liposarcoma (LPS) is a malignancy with extreme heterogeneity and thus optimization
towards personalizing patient prognosis and treatment is essential. Here, we evaluated miR …