The effects of cell therapy on heart regeneration in patients with chronic cardiomyopathy
have been assessed in several clinical trials. These trials can be categorized as those using …

With the development of tissue engineering, the required biomaterials need to have the
ability to promote cell adhesion and proliferation in vitro and in vivo. Especially, surface …

Transplantation of exogenous cardiomyocytes (CMs) is a hopeful method to treat myocardial
infarction (MI). However, its clinical application still remains challenging due to low retention …

Human pluripotent stem cell-derived cardiovascular progenitor cells (hCVPCs) and
cardiomyocytes (hCMs) possess therapeutic potential for infarcted hearts; however, their …

Background Epigenetic histone acetylation is a major event controlling cell functions, such
as metabolism, differentiation and repair. Here, we aim to determine whether Valproic acid …

Articular cartilage regeneration is a challenge in orthopedics and tissue engineering. This
study prepared a graphene oxide (GO)-modified 3D acellular cartilage extracellular matrix …

Cardiac transcription factors orchestrate a regulatory network controlling cardiovascular
development. Isl1, a LIM-homeodomain transcription factor, acts as a key player in multiple …

A comprehensive understanding of the molecular basis and mechanisms underlying cardiac
diseases is mandatory for the development of new and effective therapeutic strategies. The …

Significance: Heart failure is among the leading causes of morbidity worldwide with a 5-year
mortality rate of∼ 50%. Therefore, major efforts are invested to reduce heart damage upon …

Aims The aims of the study are to investigate whether the combination of adipose-derived
stem cells (ADSCs) with decellularized extracellular matrix (dECM) of myocardium can exert …