The pathogenesis of MS is unknown. In our studies, we have demonstrated an important
role for citrullinated myelin basic protein (MBP). The accompanying loss of positive charge …

The 18.5 kDa isoform of myelin basic protein (MBP) is a major component of the myelin
sheath in the central nervous system of higher vertebrates, and a member of a larger family …

Surfaces are the primary place of contact between a biomaterial and its host organism.
Typically, prostheses have to fulfil demanding structural and mechanical requirements, yet …

Interfacial layers are important in a wide range of applications in biomedicine, biosensing,
analytical chemistry and the maritime industries. Given the growing number of applications …

Myelin basic protein (MBP) binds to negatively charged lipids on the cytosolic surface of
oligodendrocyte membranes and is responsible for adhesion of these surfaces in the …

The degradation of myelin in the CNS is the hallmark of multiple sclerosis. Reduction in the
net positive charge of myelin basic protein (MBP), through deimination, correlates strongly …

Specific membrane microdomains (including lipid rafts) exist in myelin but have not been
fully characterized. Myelin basic protein (MBP) maintains the compactness of the myelin …

The myelin membrane comprises a plethora of regions that are compositionally,
ultrastructurally, and functionally distinct. Biochemical dissection of oligodendrocytes …

Biomolecular-membrane interactions play a critical role in the regulation of many important
biological processes such as protein trafficking, cellular signalling and ion channel …

Abstract BAR (Bin/Amphiphysin/Rvs) domain containing proteins function as lipid bilayer
benders and curvature sensors, and they contribute to membrane shaping involved in cell …