Ferroptosis is a new type of cell death that was discovered in recent years and is usually
accompanied by a large amount of iron accumulation and lipid peroxidation during the cell …

New research has shown that the development of osteoarthritis (OA) is regulated by different
mechanisms of cell death and types of cytokines. Therefore, elucidating the mechanism of …

Atherosclerosis (AS) is the fundamental pathological state of many serious vascular
diseases, characterized by disorders of lipid metabolism. Ferroptosis is a type of regulated …

Ferroptotic death is the penalty for losing control over three processes—iron metabolism,
lipid peroxidation and thiol regulation—that are common in the pro-inflammatory …

Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …

Mitochondria are fundamental for metabolic homeostasis in all multicellular eukaryotes. In
the nervous system, mitochondria-generated adenosine triphosphate (ATP) is required to …

Stimulator of interferons genes (STING), which is crucial for the secretion of type I interferons
and proinflammatory cytokines in response to cytosolic nucleic acids, plays a key role in the …

Objective Atherosclerotic vascular disease remains the principal cause of death and
disability among patients with type 2 diabetes. Unfortunately, the problem is not adequately …

Sepsis-associated encephalopathy (SAE) is a common complication of severe sepsis. Irisin
is a novel exercise-induced myokine involved in the regulation of adipose browning and …

Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …