In vitro liver cell culture models are gaining increasing importance in pharmacological and
toxicological research. The source of cells used is critical for the relevance and the …

The efficiency of clinical trials involving transplantation of multipotent mesenchymal stromal
cells (MSCs) is often insufficient due to harsh conditions present within the target tissue …

Mesenchymal stem cells (MSCs) are self-renewing multipotent cells that have the capacity to
secrete multiple biologic factors that can restore and repair injured tissues. Preclinical and …

Mesenchymal stem cells (MSCs) are stromal cells that display self-renewal and multipotent
differentiation capacity. The repertoire of mature cells generated ranges but is not restricted …

Limited by the poor proliferation and restricted sources of adult hepatocytes, there is an
urgent need to find substitutes for proliferation and cultivation of mature hepatocytes in vitro …

Modern day broilers have a great genetic potential to gain heavy bodyweights with a huge
metabolic demand prior to their fully mature ages. Moreover, this made the broilers prone to …

Progestins are a broad class of progestational agents widely differing in their chemical
structures and pharmacological properties. Despite emerging data suggest that progestins …

The human-relevance of an in vitro model is dependent on two main factors—(i) an
appropriate human cell source and (ii) a modeling platform that recapitulates human in vivo …

The insulin/insulin-like growth factor system (IIGFs) plays a fundamental role in the
regulation of prenatal and postnatal growth, metabolism and homeostasis. As a …

Intrinsic cellular properties of several types of cells are dramatically altered as the culture
condition shifts from two-dimensional (2D) to three-dimensional (3D) environment. Currently …