Chitosan derivatives and their application in biomedicine

W Wang, Q Meng, Q Li, J Liu, M Zhou, Z Jin… - International journal of …, 2020 - mdpi.com
Chitosan is a product of the deacetylation of chitin, which is widely found in nature. Chitosan
is insoluble in water and most organic solvents, which seriously limits both its application …

[HTML][HTML] Surface design of nanocarriers: Key to more efficient oral drug delivery systems

H Spleis, M Sandmeier, V Claus… - Advances in colloid and …, 2023 - Elsevier
As nanocarriers (NCs) can improve the solubility of drugs, prevent their degradation by
gastrointestinal (GI) enzymes and promote their transport across the mucus gel layer and …

Alkaline phosphatase: a reliable endogenous partner for drug delivery and diagnostics

B Le‐Vinh, ZB Akkuş‐Dağdeviren… - Advanced …, 2022 - Wiley Online Library
Since the 1960s the membrane‐bound enzyme alkaline phosphatase (ALP) has been
utilized in drug delivery. As it cleaves phosphate substructures from drugs, auxiliary agents …

Current-status and applications of polysaccharides in drug delivery systems

P Prasher, M Sharma, M Mehta, S Satija… - Colloid and Interface …, 2021 - Elsevier
The polysaccharide-based advanced drug delivery system owing to their biocompatibility,
ability to encapsulate the drug molecules in their interspaces, and ability to achieve a …

Chemical modification of polysaccharides: a review of synthetic approaches, biological activity and the structure–activity relationship

T Liu, Q Ren, S Wang, J Gao, C Shen, S Zhang… - Molecules, 2023 - mdpi.com
Natural polysaccharides are macromolecular substances with great potential owing to their
wide biological activity and low toxicity. However, not all polysaccharides have significant …

Connecting the dots in drug delivery: a tour d'horizon of chitosan-based nanocarriers system

S Pramanik, V Sali - International Journal of Biological Macromolecules, 2021 - Elsevier
One of the most promising pharmaceutical research areas is developing advanced delivery
systems for controlled and sustained drug release. The drug delivery system (DDS) can be …

[HTML][HTML] Zeta potential changing nanoemulsions based on a simple zwitterion

F Sharifi, M Jahangiri, I Nazir, MH Asim… - Journal of Colloid and …, 2021 - Elsevier
Hypothesis Simple zwitterions used as auxiliary agents might have the potential to change
the zeta potential of oil-in-water (o/w) nanoemulsions on the mucosa. Experiments The …

Improved intestinal absorption and oral bioavailability of astaxanthin using poly (ethylene glycol)‐graft‐chitosan nanoparticles: preparation, in vitro evaluation, and …

Y Zhu, Z Gu, Y Liao, S Li, Y Xue… - Journal of the …, 2022 - Wiley Online Library
BACKGROUND Astaxanthin (ASTA) is a kind of food‐derived active ingredient (FDAI) with
antioxidant and antidiabetic functions. It is nontoxic but its poor solubility and low …

Current status of N-, O-, S-heterocycles as potential alkaline phosphatase inhibitors: a medicinal chemistry overview

RS Jassas, N Naeem, A Sadiq, R Mehmood… - RSC …, 2023 - pubs.rsc.org
Heterocycles are a class of compounds that have been found to be potent inhibitors of
alkaline phosphatase (AP), an enzyme that plays a critical role in various physiological …

Design of GSH-responsive curcumin nanomicelles for oesophageal cancer therapy

Z Ma, X Gao, F Raza, H Zafar, G Huang, Y Yang, F Shi… - Pharmaceutics, 2022 - mdpi.com
Oesophageal cancer is a malignant tumor with high morbidity and mortality. Surgical
treatment, radiotherapy, and chemotherapy are the most common treatment methods for …