Decreased olfactory function is very common in the older population, being present in over
half of those between the ages of 65 and 80 years and in over three quarters of those over …

Abstract Purpose of Review The sense of smell is today one of the focuses of interest in
aging and neurodegenerative disease research. In several neurodegenerative diseases …

Objective: To determine the predictive utility of baseline odor identification deficits for future
cognitive decline and the diagnosis of Alzheimer disease (AD) dementia. Methods: In a …

Objectives To evaluate the associations between sensory impairments and 10‐year risk of
cognitive impairment. Design The Epidemiology of Hearing Loss Study (EHLS), a …

Objective We aimed to examine whether impaired olfaction is associated with cognitive
decline and indicators of neurodegeneration in the brain of dementia-free older adults …

Individual differences in cognitive performance increase with advancing age, reflecting
marked cognitive changes in some individuals along with little or no change in others …

Apolipoprotein (apo) E4 is the major genetic risk factor for Alzheimer's disease (AD),
increasing risk and decreasing age of disease onset. Many studies have demonstrated the …

Accumulating evidence suggests that Alzheimer's disease (AD) has a long preclinical
phase, during which time its characteristic pathology accumulates and patient function …

Olfaction, the sense of smell, is characterized by a notable age-dependency such that aging
individuals are more likely to have poor olfactory abilities. These impairments are …

Olfaction is a sense involved in a complex set of tasks, influencing eating behavior,
increasing awareness of environmental hazards and affecting social communication …