Breath analysis for the screening and diagnosis of diseases

N VR, AK Mohapatra, U VK, RK Sinha… - Applied Spectroscopy …, 2021 - Taylor & Francis
Exhaled breath contains small molecules and complex volatile organic compounds (VOCs)
such as H2O, CO2, NO, NH3, ketones, aldehydes, alcohols, and hydrocarbons. Analysis of …

Comb spectroscopy of CO2 produced from microbial metabolism

JA Whitaker-Lockwood, SK Scholten… - Biomedical Optics …, 2024 - opg.optica.org
We have developed a direct frequency comb spectroscopy instrument, which we have tested
on Saccharomyces cerevisiae (baker's yeast) by measuring its CO_2 output and production …

Ultrahigh-resolution direct-frequency-comb spectrometer

F Karim, SK Scholten, C Perrella, AN Luiten - Physical Review Applied, 2020 - APS
At low pressures, molecular spectra typically exhibit a large number of very narrow
absorption features spread across a relatively wide spectral bandwidth. In order to obtain an …

Precision spectroscopy of nitrous oxide isotopocules with a cross-dispersed spectrometer and a mid-infrared frequency comb

DM Bailey, G Zhao, AJ Fleisher - Analytical chemistry, 2020 - ACS Publications
As a potent greenhouse gas and an ozone-depleting agent, nitrous oxide (N2O) plays a
critical role in the global climate. Effective mitigation relies on understanding global sources …

VECSEL-based virtually imaged phased array spectrometer for rapid gas phase detection in the mid-infrared

R Rockmore, R Gibson, JV Moloney, RJ Jones - Optics Letters, 2020 - opg.optica.org
We present a novel, to the best of our knowledge, system for high-resolution, time-resolved
spectroscopy in the mid-wave infrared based on a modelocked vertical external cavity …

Accurate Optical Number Density Measurement of and with Direct Frequency Comb Spectroscopy

SK Scholten, C Perrella, JD Anstie, RT White… - Physical Review …, 2019 - APS
We report on the use of direct frequency comb spectroscopy to accurately measure the
concentrations of C 16 12 O 2 and C 16 13 O 2 isotopologs in a gas sample. We …

Compact, high-performance all-polarization-maintaining Er: fiber frequency comb with single fiber actuator

Y Cai, T Zhang, R Pan, X Hu, F Ye… - IEEE Photonics …, 2020 - ieeexplore.ieee.org
The large volume and weak environmental adaptability of fiber optical frequency combs
(OFCs) have become the main obstacles for their applications in various fields. To address …

High-resolution molecular spectroscopy and biological applications

SK Scholten, J Whitaker-Lockwood… - … on Optical Fibre …, 2019 - spiedigitallibrary.org
The rapid measurement of gas concentrations is beneficial to a broad range of applications,
including pollution monitoring, high-precision spectroscopy, and medical breath analysis …

VECSEL Frequency Combs for Mid-infrared Spectroscopy

RS Rockmore - 2020 - search.proquest.com
Frequency combs with high repetition rates above 1 GHz offer a number of advantages over
more common Mhz combs, such as higher power per comb line, more easily resolvable …

Comb tooth resolved MIR spectroscopy using a VECSEL frequency comb and a virtually-imaged phased array spectrometer

R Rockmore, R Gibson, RJ Jones… - … Lasers (VECSELs) X, 2020 - spiedigitallibrary.org
Mid infrared frequency combs allow for high resolution absorption spectroscopy of molecular
species, which have strong signatures in this spectral region. Dual comb spectroscopy can …