Ion mobility–mass spectrometry

AB Kanu, P Dwivedi, M Tam, L Matz… - Journal of mass …, 2008 - Wiley Online Library
This review article compares and contrasts various types of ion mobility–mass spectrometers
available today and describes their advantages for application to a wide range of analytes …

How useful is ion mobility mass spectrometry for structural biology? The relationship between protein crystal structures and their collision cross sections in the gas …

E Jurneczko, PE Barran - Analyst, 2011 - pubs.rsc.org
The technique of ion mobility mass spectrometry (IM-MS) has become of increasing interest
for rapid analysis of the conformations adopted by biological macromolecules. It is currently …

A cyclic ion mobility-mass spectrometry system

K Giles, J Ujma, J Wildgoose, S Pringle… - Analytical …, 2019 - ACS Publications
Improvements in the performance and availability of commercial instrumentation have made
ion mobility-mass spectrometry (IM-MS) an increasingly popular approach for the structural …

[图书][B] Ion mobility spectrometry

GA Eiceman, Z Karpas - 2005 - taylorfrancis.com
Key Developments for Faster, More Precise Detection Capabilities Driven by the demand for
the rapid and advanced detection of explosives, chemical and biological warfare agents …

An investigation of the mobility separation of some peptide and protein ions using a new hybrid quadrupole/travelling wave IMS/oa-ToF instrument

SD Pringle, K Giles, JL Wildgoose, JP Williams… - International Journal of …, 2007 - Elsevier
Ion mobility coupled with mass spectrometry has evolved into a powerful analytical
technique for investigating the gas-phase structures of bio-molecules. Here we present the …

Resolution of isomeric mixtures in ion mobility using a combined demultiplexing and peak deconvolution technique

JC May, R Knochenmuss, JC Fjeldsted… - Analytical …, 2020 - ACS Publications
A combined data acquisition and data processing strategy for improving the sensitivity and
resolution of ion mobility measurements is described. This strategy is implemented on a …

Gas-phase separation using a trapped ion mobility spectrometer

F Fernandez-Lima, DA Kaplan, J Suetering… - International Journal for …, 2011 - Springer
In the present work we describe the principles of operation, versatility and applicability of a
trapped ion mobility spectrometer (TIMS) analyzer for fast, gas-phase separation of …

Ion mobility collision cross section compendium

JC May, CB Morris, JA McLean - Analytical chemistry, 2017 - ACS Publications
In this Review, we focus on an important aspect of ion mobility (IM) research, namely, the
reporting of quantitative ion mobility measurements in the form of the gas-phase collision …

Protein complexes in the gas phase: technology for structural genomics and proteomics

JLP Benesch, BT Ruotolo, DA Simmons… - Chemical …, 2007 - ACS Publications
How does the development of mass spectrometry (MS) for the study of protein complexes,
intact in the gas phase, contribute to the twin fields of genomics and proteomics? Foremost …

Deciphering drift time measurements from travelling wave ion mobility spectrometry-mass spectrometry studies

DP Smith, TW Knapman, I Campuzano… - European journal of …, 2009 - journals.sagepub.com
Detailed knowledge of the tertiary and quaternary structure of proteins and protein
complexes is of immense importance in understanding their functionality. Similarly …