Vascular calcification is associated with a significant increase in all-cause mortality and
atherosclerotic plaque rupture. Calcification has been determined to be an active process …

Calcific aortic stenosis (AS) is the most prevalent heart valve disorder in developed
countries. It is characterized by progressive fibro-calcific remodelling and thickening of the …

Aortic valve stenosis is the most prevalent heart valve disease worldwide. Although
interventional treatment options have rapidly improved in recent years, symptomatic aortic …

Calcific aortic valve disease (CAVD) is the most common disorder affecting heart valves and
is characterized by thickening, fibrosis and mineralization of the aortic valve leaflets …

In the past decade, the prevalence, significance, and regulatory mechanisms of vascular
calcification have gained increasing recognition. Over a century ago, pathologists …

Cardiovascular complications are the leading cause of death in patients with chronic kidney
disease (CKD). Vascular calcification is a common complication in CKD, and investigators …

Oxidative stress plays a critical role in the pathogenesis of atherosclerosis including the
formation of lipid laden macrophages and the development of inflammation. However …

Vascular mineralization has recently emerged as a risk factor for cardiovascular morbidity
and mortality. Previously regarded as a passive end-stage process, vascular mineralization …

Background—Vascular calcification is associated with increased morbidity and mortality in
stage V chronic kidney disease, yet its early pathogenesis and initiating mechanisms in vivo …

Calcific aortic valve stenosis (CAVS) is a major health problem facing aging societies. The
identification of osteoblast-like and osteoclast-like cells in human tissue has led to a major …