Direct and cell-mediated EV-ECM interplay
Extracellular vesicles (EV) are a heterogeneous group of lipid particles excreted by cells.
They play an important role in regeneration, development, inflammation, and cancer …
They play an important role in regeneration, development, inflammation, and cancer …
Invited Review for 20th Anniversary Special Issue of PLRev “AI for Mechanomedicine”
Mechanomedicine is a field that combines different areas including biomechanics,
mechanobiology, and clinical applications like mechanodiagnosis and mechanotherapy …
mechanobiology, and clinical applications like mechanodiagnosis and mechanotherapy …
Automated bio-AFM generation of large mechanome data set and their analysis by machine learning to classify cancerous cell lines
O Thomas--Chemin, C Séverac… - … Applied Materials & …, 2024 - ACS Publications
Mechanobiological measurements have the potential to discriminate healthy cells from
pathological cells. However, a technology frequently used to measure these properties, ie …
pathological cells. However, a technology frequently used to measure these properties, ie …
Indentation of living cells by AFM tips may not be what we thought!
The models used to calculate Young's moduli from atomic force microscopy (AFM) force
curves consider the shape of the indentation. It is then assumed that the geometry of the …
curves consider the shape of the indentation. It is then assumed that the geometry of the …
Free energy calculations for membrane morphological transformations and insights to physical biology and oncology
In this chapter, we aim to bridge basic molecular and cellular principles surrounding
membrane curvature generation with rewiring of cellular signals in cancer through …
membrane curvature generation with rewiring of cellular signals in cancer through …
[HTML][HTML] Asymmetric Crowders and Membrane Morphology at the Nexus of Intracellular Trafficking and Oncology
A definitive understanding of the interplay between protein binding/migration and membrane
curvature evolution is emerging but needs further study. The mechanisms defining such …
curvature evolution is emerging but needs further study. The mechanisms defining such …