DYM Leung, E Guttman-Yassky - Journal of Allergy and Clinical …, 2014 - Elsevier
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. It often precedes the development of food allergy and asthma. Recent insights into AD reveal …
T Matsui, M Amagai - International immunology, 2015 - academic.oup.com
The skin is the largest organ of the mammalian body. The outermost layer of mammalian skin, the stratum corneum (SC) of the epidermis, consists of piles of dead corneocytes that …
Background Atopic dermatitis (AD) is a chronic inflammatory disease caused by the complex interaction of genetic, immune and environmental factors. There have many recent …
Atopic dermatitis (AD) is the most common allergic skin disease in the general population. It is a chronic inflammatory skin disease complicated by recurrent bacterial and viral infections …
JP Thyssen, S Kezic - Journal of Allergy and Clinical Immunology, 2014 - Elsevier
The epidermis protects human subjects from exogenous stressors and helps to maintain internal fluid and electrolyte homeostasis. Filaggrin is a crucial epidermal protein that is …
G Egawa, K Kabashima - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Atopic dermatitis (AD) is the most common inflammatory skin disease in the industrialized world and has multiple causes. Over the past decade, data from both experimental models …
MR Mack, BS Kim - Trends in immunology, 2018 - cell.com
Relentless, repetitive itching and scratching is a debilitating feature of many chronic inflammatory skin disorders such as atopic dermatitis. While well known clinically, this itch …
G Egawa, K Kabashima - Allergology international, 2018 - jstage.jst.go.jp
abstract The skin is continuously exposed to external pathogens, and its barrier function is critical for skin homeostasis. Previous studies have shown that the barrier dysfunction is one …
A Otsuka, T Nomura, P Rerknimitr… - Immunological …, 2017 - Wiley Online Library
Atopic dermatitis (AD) is a chronic skin disorder characterized by pruritus and recurrent eczematous lesions that are accompanied by T‐helper (Th) 2‐dominated inflammation. AD …