With the advent of the genetic era in Parkinson's disease (PD) research in 1997, α-synuclein
was identified as an important player in a complex neurodegenerative disease that affects> …

Neurodegenerative diseases such as Parkinson's disease (PD) are manifested by inclusion
bodies of alpha-synuclein (α-syn) also called α-synucleinopathies. Detection of these …

Parkinson's disease (PD) is a neurodegenerative disorder that affects millions of people
worldwide. Two hallmarks of PD are the accumulation of alpha‐synuclein and the loss of …

The accumulation of amyloid fibrils is characteristic of neurodegenerative diseases such as
Alzheimer's disease (AD) and Parkinson's disease. Detecting these fibrils with fluorescent or …

Purpose Deposition of misfolded alpha-synuclein (αSYN) aggregates in the human brain is
one of the major hallmarks of synucleinopathies. However, a target-specific tracer to detect …

ABSTRACT α‐Synucleinopathies including idiopathic Parkinson's disease, dementia with
Lewy bodies and multiple systems atrophy share overlapping symptoms and pathological …

Cytoplasmic deposition of aberrantly misfolded α-synuclein (α-Syn) is a common feature of
synucleinopathies, including Parkinson's disease (PD). However, the precise pathogenic …

Radiolabelling small molecules with beta-emitters has been intensively explored in the last
decades and novel concepts for the introduction of radionuclides continue to be reported …

Dementia with Lewy bodies (DLB) is neuropathologically defined by the presence of α-
synuclein aggregates, but many DLB cases show concurrent Alzheimer's disease pathology …

Parkinson's disease (PD) is a threatening neurodegenerative disorder that seriously affects
patients' life quality. Substantial evidence links the overexpression and abnormal …