Multifaceted genes in amyotrophic lateral sclerosis-frontotemporal dementia
R Ranganathan, S Haque, K Coley… - Frontiers in …, 2020 - frontiersin.org
Amyotrophic lateral sclerosis and frontotemporal dementia are two progressive, adult onset
neurodegenerative diseases, caused by the cell death of motor neurons in the motor cortex …
neurodegenerative diseases, caused by the cell death of motor neurons in the motor cortex …
Advances in sequencing technologies for amyotrophic lateral sclerosis research
Amyotrophic lateral sclerosis (ALS) is caused by upper and lower motor neuron loss and
has a fairly rapid disease progression, leading to fatality in an average of 2-5 years after …
has a fairly rapid disease progression, leading to fatality in an average of 2-5 years after …
Ubiquitin homeostasis is disrupted in TDP-43 and FUS cell models of ALS
A major feature of amyotrophic lateral sclerosis (ALS) pathology is the accumulation of
ubiquitin (Ub) into intracellular inclusions. This sequestration of Ub may reduce the …
ubiquitin (Ub) into intracellular inclusions. This sequestration of Ub may reduce the …
Roles of m6A modification in neurological diseases.
Y Zhang, S Zhang, M Shi, M Li, J Zeng… - … nan da xue xue bao. Yi …, 2022 - europepmc.org
Abstract N6-甲基腺苷 (N6-methyladenosine, m6A) 甲基化修饰是真核生物 mRNA
最常见的表观遗传修饰之一, 在相关酶的催化调控下, m6A 通过介导 RNA 转录, 剪接, 翻译 …
最常见的表观遗传修饰之一, 在相关酶的催化调控下, m6A 通过介导 RNA 转录, 剪接, 翻译 …
[HTML][HTML] m6A 修饰在神经系统疾病中的作用
张圆， 张巳， 时萌萌， 李梦琳， 曾佳玉… - Journal of Central South …, 2022 - ncbi.nlm.nih.gov
Abstract N6-甲基腺苷(N6-methyladenosine， m6A) 甲基化修饰是真核生物mRNA
最常见的表观遗传修饰之一， 在相关酶的催化调控下， m6A 通过介导RNA 转录、 剪接、 翻译 …
最常见的表观遗传修饰之一， 在相关酶的催化调控下， m6A 通过介导RNA 转录、 剪接、 翻译 …