Epidemiology of the inherited cardiomyopathies

WJ McKenna, DP Judge - Nature Reviews Cardiology, 2021 - nature.com
In the absence of contemporary, population-based epidemiological studies, estimates of the
incidence and prevalence of the inherited cardiomyopathies have been derived from …

Arrhythmogenic cardiomyopathy

D Corrado, C Basso, DP Judge - Circulation research, 2017 - Am Heart Assoc
Arrhythmogenic cardiomyopathy is an inherited heart muscle disorder, predisposing to
sudden cardiac death, particularly in young patients and athletes. Pathological features …

2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy

JA Towbin, WJ McKenna, DJ Abrams, MJ Ackerman… - Heart rhythm, 2019 - Elsevier
Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium
not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a …

HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies: this document was developed as a partnership …

MJ Ackerman, SG Priori, S Willems, C Berul… - Europace, 2011 - academic.oup.com
1From Mayo Clinic, Rochester, Minnesota; 2Fondazione Salvatore Maugeri University of
Pavia, Pavia, Italy and New York University, New York, New York; 3University Hospital …

[HTML][HTML] Overview of the muscle cytoskeleton

CA Henderson, CG Gomez, SM Novak… - Comprehensive …, 2017 - ncbi.nlm.nih.gov
Cardiac and skeletal striated muscles are intricately designed machines responsible for
muscle contraction. Coordination of the basic contractile unit, the sarcomere, and the …

Exercise increases age-related penetrance and arrhythmic risk in arrhythmogenic right ventricular dysplasia/cardiomyopathy–associated desmosomal mutation …

CA James, A Bhonsale, C Tichnell, B Murray… - Journal of the American …, 2013 - jacc.org
Objectives: This study sought to determine how exercise influences penetrance of
arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) among patients with …

Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: proposed modification of the task force criteria

FI Marcus, WJ McKenna, D Sherrill, C Basso, B Bauce… - Circulation, 2010 - Am Heart Assoc
Background—In 1994, an International Task Force proposed criteria for the clinical
diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) that …

Impact of genotype on clinical course in arrhythmogenic right ventricular dysplasia/cardiomyopathy-associated mutation carriers

A Bhonsale, JA Groeneweg, CA James… - European heart …, 2015 - academic.oup.com
Aims We sought to determine the influence of genotype on clinical course and arrhythmic
outcome among arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) …

Exercise has a disproportionate role in the pathogenesis of arrhythmogenic right ventricular dysplasia/cardiomyopathy in patients without desmosomal mutations

AC Sawant, A Bhonsale, ASJM te Riele… - Journal of the …, 2014 - Am Heart Assoc
Background Exercise is associated with age‐related penetrance and arrhythmic risk in
carriers of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C)‐associated …

[HTML][HTML] Desmosome structure, composition and function

D Garrod, M Chidgey - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2008 - Elsevier
Desmosomes are intercellular junctions of epithelia and cardiac muscle. They resist
mechanical stress because they adopt a strongly adhesive state in which they are said to be …