Breast cancer is the most common malignancy among females. 5%–10% of breast cancer
cases are hereditary and are caused by pathogenic mutations in the considered reference …

OBJECTIVES: Peutz–Jeghers syndrome (PJS) is an autosomal dominant inherited disorder
associated with increased cancer risk. Surveillance and patient management are, however …

Background & Aims: The Peutz–Jeghers syndrome (PJS) is an autosomal dominant
polyposis disorder with increased risk of multiple cancers, but literature estimates of risk …

Background: Although an increased cancer risk in Peutz-Jeghers syndrome is established,
data on the spectrum of tumors associated with the disease and the influence of germ-line …

The past two decades have brought many important advances in our understanding of the
hereditary susceptibility to cancer. Approximately 5–10% of all cancers are inherited, the …

The plant hormone indole-3 acetic acid (IAA or auxin) controls many aspects of plant
development, including the production of lateral roots,,. Ubiquitin-mediated proteolysis has a …

Background & Aims: Individuals with a strong family history of pancreatic cancer and
persons with Peutz-Jeghers syndrome (PJS) have an increased risk for pancreatic cancer …

Peutz-Jeghers syndrome (PJS) is an autosomal dominant disease caused by germline
mutation of the serine threonine kinase 11 and characterized by hamartomatous polyps in …

PURPOSE: The mucosa of the small intestine encompasses about 90% of the luminal
surface area of the digestive system, but only 2% of the total annual gastrointestinal cancer …

Background & Aims: Relatives of patients with pancreatic cancer and persons with certain
inherited syndromes are at increased risk for developing pancreatic cancer. We …