While many of the cardiac limitations to exercise performance are now well-characterized,
extracardiac limitations to exercise performance have been less well recognized but are …

Background Resistant hypertension is highly prevalent among the general hypertensive
population and the clinical management of this condition remains problematic. Different …

Background: Arterial hypertension is the most common comorbidity in patients with heart
failure with preserved ejection fraction (HFpEF) and mediates adverse hemodynamics …

Background Splanchnic nerve modulation (SNM) is an emerging procedure to reduce
cardiac filling pressures in heart failure. Although the main contributor to reduction in cardiac …

The blood pressure (BP) lowering response to renal denervation (RDN) remains variable
with about one-third of patients not responding to ultrasound or radiofrequency RDN …

Improved and durable control of hypertension is a global priority for healthcare providers
and policymakers. There are several lifestyle measures that are proven to result in improved …

The evolution of renal denervation (RDN) has now come full circle. When catheter-based
RDN was first conceived, it was explored as a treatment to overcome diuretic resistance in …

Objective: The effect of renal denervation (RDN) on heart rate (HR) in patients with
hypertension had been investigated in many studies, but the results were inconsistent. This …

Recent trial results support catheter-based renal denervation (RDN) for treatment of
hypertension, while the exact mechanisms causing blood pressure to fall remain …

A hallmark of heart failure (HF), whether it presents itself during rest or periods of physical
exertion, is the excessive elevation of intracardiac filling pressures at rest or with exercise …