Advances in lipid extraction methods—a review
Extraction of lipids from biological tissues is a crucial step in lipid analysis. The selection of
appropriate solvent is the most critical factor in the efficient extraction of lipids. A mixture of …
appropriate solvent is the most critical factor in the efficient extraction of lipids. A mixture of …
Toward merging untargeted and targeted methods in mass spectrometry-based metabolomics and lipidomics
Advances in mass spectrometry (MS) and data processing have led to discoveries in
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …
Ms-based lipidomics of human blood plasma: A community-initiated position paper to develop accepted guidelines1
Human blood is a self-regenerating lipid-rich biological fluid that is routinely collected in
hospital settings. The inventory of lipid molecules found in blood plasma (plasma lipidome) …
hospital settings. The inventory of lipid molecules found in blood plasma (plasma lipidome) …
High-throughput plasma lipidomics: detailed mapping of the associations with cardiometabolic risk factors
High-throughput targeted lipid profiling with liquid chromatography-mass spectrometry (LC-
MS) has been used extensively to identify associations between plasma lipid species and …
MS) has been used extensively to identify associations between plasma lipid species and …
Recent advances in LC‐MS‐based metabolomics for clinical biomarker discovery
The employment of liquid chromatography‐mass spectrometry (LC‐MS) untargeted and
targeted metabolomics has led to the discovery of novel biomarkers and improved the …
targeted metabolomics has led to the discovery of novel biomarkers and improved the …
Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease
We integrated lipidomics and genomics to unravel the genetic architecture of lipid
metabolism and identify genetic variants associated with lipid species putatively in the …
metabolism and identify genetic variants associated with lipid species putatively in the …
High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies
Obesity and related metabolic diseases show clear sex-related differences. The growing
burden of these diseases calls for better understanding of the age-and sex-related metabolic …
burden of these diseases calls for better understanding of the age-and sex-related metabolic …
Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease
Abstract Changes to lipid metabolism are tightly associated with the onset and pathology of
Alzheimer's disease (AD). Lipids are complex molecules comprising many isomeric and …
Alzheimer's disease (AD). Lipids are complex molecules comprising many isomeric and …
Plasma lipidomic profiles improve on traditional risk factors for the prediction of cardiovascular events in type 2 diabetes mellitus
Background: Clinical lipid measurements do not show the full complexity of the altered lipid
metabolism associated with diabetes mellitus or cardiovascular disease. Lipidomics enables …
metabolism associated with diabetes mellitus or cardiovascular disease. Lipidomics enables …
Dysregulation of lipids in Alzheimer's disease and their role as potential biomarkers
The brain is highly enriched in lipids, and an intensive study of these lipids may be
informative, not only of normal brain function but also of changes with age and in disease. In …
informative, not only of normal brain function but also of changes with age and in disease. In …