The assembly of functional neural circuits requires the combined action of progressive and regressive events. Regressive events encompass a variety of inhibitory developmental …
HB Wang, H Zhang, JP Zhang, Y Li, B Zhao… - Nature …, 2015 - nature.com
Epstein–Barr virus (EBV) is implicated as an aetiological factor in B lymphomas and nasopharyngeal carcinoma. The mechanisms of cell-free EBV infection of nasopharyngeal …
Proper brain wiring during development is pivotal for adult brain function. Neurons display a high degree of polarization both morphologically and functionally, and this polarization …
O Schuldiner, A Yaron - Cellular and Molecular Life Sciences, 2015 - Springer
The precise wiring of the nervous system is a combined outcome of progressive and regressive events during development. Axon guidance and synapse formation intertwined …
The primary motor cortex (M1) is essential for voluntary fine motor control and is functionally conserved across mammals. Using high-throughput transcriptomic and epigenomic profiling …
M Laurin, JF Côté - Genes & development, 2014 - genesdev.cshlp.org
Rho GTPases play key regulatory roles in many aspects of embryonic development, regulating processes such as differentiation, proliferation, morphogenesis, and migration …
Myelin is formed by specialized myelinating glia: oligodendrocytes and Schwann cells in the central and peripheral nervous systems, respectively. While there are distinct developmental …
E Koropouli, AL Kolodkin - Current opinion in neurobiology, 2014 - Elsevier
Highlights•Semaphorins affect the spatial distribution of synapses by regulating dendritic arborization.•Semaphorins directly affect the formation of excitatory and inhibitory …