Semaphorins and their signaling mechanisms

LT Alto, JR Terman - Semaphorin Signaling: Methods and Protocols, 2017 - Springer
Semaphorins are extracellular signaling proteins that are essential for the development and
maintenance of many organs and tissues. The more than 20-member semaphorin protein …

Sculpting neural circuits by axon and dendrite pruning

MM Riccomagno, AL Kolodkin - Annual review of cell and …, 2015 - annualreviews.org
The assembly of functional neural circuits requires the combined action of progressive and
regressive events. Regressive events encompass a variety of inhibitory developmental …

Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells

HB Wang, H Zhang, JP Zhang, Y Li, B Zhao… - Nature …, 2015 - nature.com
Epstein–Barr virus (EBV) is implicated as an aetiological factor in B lymphomas and
nasopharyngeal carcinoma. The mechanisms of cell-free EBV infection of nasopharyngeal …

[HTML][HTML] Cell biology in neuroscience: Cellular and molecular mechanisms underlying axon formation, growth, and branching

TL Lewis Jr, J Courchet, F Polleux - The Journal of cell biology, 2013 - ncbi.nlm.nih.gov
Proper brain wiring during development is pivotal for adult brain function. Neurons display a
high degree of polarization both morphologically and functionally, and this polarization …

Mechanisms of developmental neurite pruning

O Schuldiner, A Yaron - Cellular and Molecular Life Sciences, 2015 - Springer
The precise wiring of the nervous system is a combined outcome of progressive and
regressive events during development. Axon guidance and synapse formation intertwined …

Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse

TE Bakken, NL Jorstad, Q Hu, BB Lake, W Tian… - BioRxiv, 2020 - biorxiv.org
The primary motor cortex (M1) is essential for voluntary fine motor control and is functionally
conserved across mammals. Using high-throughput transcriptomic and epigenomic profiling …

Insights into the biological functions of Dock family guanine nucleotide exchange factors

M Laurin, JF Côté - Genes & development, 2014 - genesdev.cshlp.org
Rho GTPases play key regulatory roles in many aspects of embryonic development,
regulating processes such as differentiation, proliferation, morphogenesis, and migration …

On and off retinal circuit assembly by divergent molecular mechanisms

LO Sun, Z Jiang, M Rivlin-Etzion, R Hand, CM Brady… - Science, 2013 - science.org
Introduction Direction-selective responses to visual cues depend upon precise connectivity
between inhibitory starburst amacrine cells (SACs) and direction-selective ganglion cells …

Differential Sox10 genomic occupancy in myelinating glia

C Lopez‐Anido, G Sun, M Koenning, R Srinivasan… - Glia, 2015 - Wiley Online Library
Myelin is formed by specialized myelinating glia: oligodendrocytes and Schwann cells in the
central and peripheral nervous systems, respectively. While there are distinct developmental …

Semaphorins and the dynamic regulation of synapse assembly, refinement, and function

E Koropouli, AL Kolodkin - Current opinion in neurobiology, 2014 - Elsevier
Highlights•Semaphorins affect the spatial distribution of synapses by regulating dendritic
arborization.•Semaphorins directly affect the formation of excitatory and inhibitory …