Rodent models of focal cerebral ischemia: procedural pitfalls and translational problems
S Braeuninger, C Kleinschnitz - Experimental & translational stroke …, 2009 - Springer
Rodent models of focal cerebral ischemia are essential tools in experimental stroke
research. They have added tremendously to our understanding of injury mechanisms in …
research. They have added tremendously to our understanding of injury mechanisms in …
A critical reevaluation of the intraluminal thread model of focal cerebral ischemia: evidence of inadvertent premature reperfusion and subarachnoid hemorrhage in rats …
R Schmid-Elsaesser, S Zausinger, E Hungerhuber… - Stroke, 1998 - Am Heart Assoc
Background and Purpose—The intraluminal thread model for middle cerebral artery
occlusion (MCAO) has gained increasing acceptance. Numerous modifications have been …
occlusion (MCAO) has gained increasing acceptance. Numerous modifications have been …
Core and penumbral nitric oxide synthase activity during cerebral ischemia and reperfusion
S Ashwal, B Tone, HR Tian, DJ Cole, WJ Pearce - Stroke, 1998 - Am Heart Assoc
Background and Purpose—The present studies examined the hypothesis that the
distribution of cerebral injury after a focal ischemic insult is associated with the regional …
distribution of cerebral injury after a focal ischemic insult is associated with the regional …
Cerebral ischemia: from animal studies to clinical practice. Should the methods be reviewed?
MA de Leciñana, E Díez-Tejedor, F Carceller… - Cerebrovascular …, 2001 - karger.com
The development of experimental models of focal cerebral ischemia has allowed for a better
knowledge of its pathophysiology and for testing therapeutic strategies. However, most …
knowledge of its pathophysiology and for testing therapeutic strategies. However, most …
Risk factors and outcome of patients with carotid artery stenosis presenting with lacunar stroke
D Inzitari, M Eliasziw, BL Sharpe, AJ Fox, HJM Barnett… - Neurology, 2000 - AAN Enterprises
Objective: To examine the relationship between carotid artery stenosis, other risk factors,
and lacunar stroke. Background: Carotid artery stenosis in patients presenting with lacune …
and lacunar stroke. Background: Carotid artery stenosis in patients presenting with lacune …
Prereperfusion saline infusion into ischemic territory reduces inflammatory injury after transient middle cerebral artery occlusion in rats
Y Ding, J Li, JA Rafols, JW Phillis, FG Diaz - Stroke, 2002 - Am Heart Assoc
Background and Purpose—In ischemic stroke, the ischemic crisis activates a cascade of
events that are potentiated by reperfusion, eventually leading to cell death. The chief aim in …
events that are potentiated by reperfusion, eventually leading to cell death. The chief aim in …
Anesthetic methods in rats determine outcome after experimental focal cerebral ischemia: mechanical ventilation is required to obtain controlled experimental …
S Zausinger, A Baethmann, R Schmid-Elsaesser - Brain research protocols, 2002 - Elsevier
Objective: Anesthetic agents, pH, blood gases and blood pressure have all been found to
influence the pathophysiology of experimental stroke. In experimental research, rats are …
influence the pathophysiology of experimental stroke. In experimental research, rats are …
Thrombolysis with intravenous rtPA in a series of 100 cases of acute carotid territory stroke: determination of etiological, topographic, and radiological outcome factors
P Trouillas, N Nighoghossian, L Derex, P Adeleine… - Stroke, 1998 - Am Heart Assoc
Background and Purpose—Although new, large, double-blind, randomized studies are
needed to establish the efficiency of intravenous thrombolysis, open trials of sufficient size …
needed to establish the efficiency of intravenous thrombolysis, open trials of sufficient size …
Progressive impairment of brain oxidative metabolism reversed by reperfusion following middle cerebral artery occlusion in anaesthetized baboons
O Touzani, AR Young, JM Derlon, JC Baron… - Brain research, 1997 - Elsevier
A better understanding of the temporospatial evolution of ischaemic brain tissue towards
necrosis would be of crucial value to establish and validate therapeutic strategies for stroke …
necrosis would be of crucial value to establish and validate therapeutic strategies for stroke …
Combined perfusion and diffusion-weighted magnetic resonance imaging in a rat model of reversible middle cerebral artery occlusion
TB Müller, O Haraldseth, RA Jones, G Sebastiani… - Stroke, 1995 - Am Heart Assoc
Background and Purpose Diffusion-weighted imaging and dynamic first-pass bolus tracking
of susceptibility contrast agents (perfusion imaging) are two new magnetic resonance …
of susceptibility contrast agents (perfusion imaging) are two new magnetic resonance …