Bacterial transition metal homoeostasis or simply 'metallostasis' describes the process by
which cells control the intracellular availability of functionally required metal cofactors, from …

Allostery is a ubiquitous biological regulatory process in which distant binding sites within a
protein or enzyme are functionally and thermodynamically coupled. Allosteric interactions …

Metal ions play significant roles in biological systems. Accurate molecular dynamics (MD)
simulations on these systems require a validated set of parameters. Although there are more …

Highlights•The 'fight over copper and zinc'at the host–pathogen interface is
discussed.•Proteins involved in copper and zinc trafficking and sensing are …

Allostery is a ubiquitous biological mechanism in which a distant binding site is coupled to
and drastically alters the function of a catalytic site in a protein. Allostery provides a high …

Biosensors are analytical tools with a great application in healthcare, food quality control,
and environmental monitoring. They are of considerable interest to be designed by using …

Highlights•Key interaction features due to metal binding in metalloproteins were
discussed.•Progress on molecular simulations of metalloprotein folding with diverse models …

Arsenic is highly toxic and a significant threat to human health, but certain bacteria have
developed defense mechanisms initiated by AsIII binding to AsIII-sensing proteins of the …

Allostery is a regulatory phenomenon whereby ligand binding to one site influences the
binding of the same or a different ligand to another site on a macromolecule. The physical …

MarR (multiple antibiotic resistance repressor) family proteins are bacterial repressors that
regulate transcription in response to a wide range of chemical signals. Although specific …