[HTML][HTML] Integration strategies of multi-omics data for machine learning analysis
Increased availability of high-throughput technologies has generated an ever-growing
number of omics data that seek to portray many different but complementary biological …
number of omics data that seek to portray many different but complementary biological …
Integrated multi-omics analyses in oncology: a review of machine learning methods and tools
In recent years, high-throughput sequencing technologies provide unprecedented
opportunity to depict cancer samples at multiple molecular levels. The integration and …
opportunity to depict cancer samples at multiple molecular levels. The integration and …
Global mapping of cancers: The Cancer Genome Atlas and beyond
Cancer genomes have been explored from the early 2000s through massive exome
sequencing efforts, leading to the publication of The Cancer Genome Atlas in 2013 …
sequencing efforts, leading to the publication of The Cancer Genome Atlas in 2013 …
The p53 family member p73 in the regulation of cell stress response
JM Rozenberg, S Zvereva, A Dalina, I Blatov, I Zubarev… - Biology direct, 2021 - Springer
During oncogenesis, cells become unrestrictedly proliferative thereby altering the tissue
homeostasis and resulting in subsequent hyperplasia. This process is paralleled by …
homeostasis and resulting in subsequent hyperplasia. This process is paralleled by …
Can COVID-19 pandemic boost the epidemic of neurodegenerative diseases?
Abstract The pandemic of Coronavirus Disease 2019 (COVID-19) presents the world with
the medical challenge associated with multifactorial nature of this pathology. Indeed COVID …
the medical challenge associated with multifactorial nature of this pathology. Indeed COVID …
Liquid biopsies and cancer omics
The development of the sequencing technologies allowed the generation of huge amounts
of molecular data from a single cancer specimen, allowing the clinical oncology to enter the …
of molecular data from a single cancer specimen, allowing the clinical oncology to enter the …
Low level of plasminogen increases risk for mortality in COVID-19 patients
D Della-Morte, F Pacifici, C Ricordi, R Massoud… - Cell death & …, 2021 - nature.com
The pathophysiology of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), and especially of its complications is still …
respiratory syndrome coronavirus 2 (SARS-CoV-2), and especially of its complications is still …
A deep learning-based framework for predicting survival-associated groups in colon cancer by integrating multi-omics and clinical data
Precise prognostic classification of patients and identifying survival subgroups and their
associated genes can be important clinical references when designing treatment strategies …
associated genes can be important clinical references when designing treatment strategies …
Cancer predictive studies
The identification of individual or clusters of predictive genetic alterations might help in
defining the outcome of cancer treatment, allowing for the stratification of patients into …
defining the outcome of cancer treatment, allowing for the stratification of patients into …
NUAK2 and RCan2 participate in the p53 mutant pro-tumorigenic network
E Mammarella, C Zampieri, E Panatta, G Melino… - Biology Direct, 2021 - Springer
Most inactivating mutations in TP53 gene generates neomorphic forms of p53 proteins that
experimental evidence and clinical observations suggest to exert gain-of-function effects …
experimental evidence and clinical observations suggest to exert gain-of-function effects …