Taking a strand: Aptamers are small single‐stranded oligonucleotides that fold into a well‐
defined 3D structure and interact with high affinity and specificity with their target molecules …

Single-stranded oligonucleotide aptamers have attracted great attention in the past decade
because of their diagnostic and therapeutic potential. These versatile, high affinity and …

The yeast two-hybrid system pioneered the field of in vivo protein-protein interaction
methods and undisputedly gave rise to a palette of ingenious techniques that are constantly …

The maize pathogen Ustilago maydis has to undergo various morphological transitions for
the completion of its sexual life cycle. For example, haploid cells respond to pheromone by …

Single-stranded DNA or RNA aptamer molecules have usually been selected against
purified target molecules. To eliminate the need of purifying target molecules on the cell …

DNA aptamers specifically recognizing microbial cells and viruses have a range of analytical
and therapeutic applications. This article describes recent advances in the development of …

Cytoskeletal transport promotes polar growth in filamentous fungi. In Ustilago maydis, the
RNA‐binding protein Rrm4 shuttles along microtubules and is crucial for polarity in …

The first conditional gene expression system which employed a small molecule binding
aptamer was developed several years before the discovery of natural riboswitches. With the …

RNA‐binding proteins (RBPs) determine spatiotemporal gene expression by mediating
active transport and local translation of cargo mRNAs. Here, we cast a transcriptome‐wide …

Hepatocellular carcinoma (HCC) is one of the most common cancers with a high mortality
rate. Late diagnosis and poor prognosis are still a major drawback since curative therapies …