Abstract SARS-CoV-2, like other coronaviruses, builds a membrane-bound replication
organelle to enable RNA replication. The SARS-CoV-2 replication organelle is composed of …

While the antibody response to SARS-CoV-2 has been extensively studied in blood,
relatively little is known about the antibody response in saliva and its relationship to systemic …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently identified
coronavirus that causes the respiratory disease known as coronavirus disease 2019 (COVID …

Activation of the RIG-I-like receptors, retinoic-acid inducible gene I (RIG-I) and melanoma
differentiation-associated protein 5 (MDA5), establishes an antiviral state by upregulating …

Understanding the mechanisms of coronavirus disease 2019 (COVID-19) disease severity
to efficiently design therapies for emerging virus variants remains an urgent challenge of the …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs)
possess mutations that confer resistance to neutralizing antibodies within the Spike protein …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein is
essential for viral replication, making it a promising target for antiviral drug and vaccine …

Viral replication is dependent on interactions between viral polypeptides and host proteins.
Identifying virus-host protein interactions can thus uncover unique opportunities for …

The multidomain non-structural protein 3 (Nsp3) is the largest protein encoded by
coronavirus (CoV) genomes and several regions of this protein are essential for viral …

Coronaviruses are large positive-sense RNA viruses with spike-like peplomers on their
surface. The Coronaviridae family's strains infect different animals and are popularly …