The headgroup evolution of cationic lipids for gene delivery

D Zhi, S Zhang, S Cui, Y Zhao, Y Wang… - Bioconjugate …, 2013 - ACS Publications
Cationic lipids are one of the most widely used nonviral vectors for gene delivery and are
especially attractive because they can be easily synthesized and extensively characterized …

A review on cationic lipids with different linkers for gene delivery

D Zhi, Y Bai, J Yang, S Cui, Y Zhao, H Chen… - Advances in colloid and …, 2018 - Elsevier
Cationic lipids have become known as one of the most versatile tools for the delivery of
DNA, RNA and many other therapeutic molecules, and are especially attractive because …

Updates in bile acid-bioactive molecule conjugates and their applications

R Mishra, S Mishra - Steroids, 2020 - Elsevier
Bile acid conjugates are emerging as important chemical resources due to their low cost and
wide availability of bile acids, making them privileged molecules in drug carrier systems and …

The chemistry and biology of organic guanidine derivatives

RGS Berlinck, AE Trindade-Silva… - Natural Product …, 2012 - pubs.rsc.org
Covering: 2010 and 2011. Previous review: Nat. Prod. Rep., 2010, 27, 1871 The chemistry
and biology of organic natural guanidines are reviewed, including the isolation, structure …

Combinatorial library strategies for synthesis of cationic lipid-like nanoparticles and their potential medical applications

S Altınoglu, M Wang, Q Xu - Nanomedicine, 2015 - Taylor & Francis
The past two decades have witnessed the high efficiency and efficacy of cationic lipids and
liposomal formations for drug delivery. The tedious synthesis of conventional lipids and the …

Cationic liposomes as gene delivery system: transfection efficiency and new application

F Xiong, Z Mi, N Gu - Die Pharmazie-An International Journal of …, 2011 - ingentaconnect.com
As it has been generally reported that oppositely charged cationic liposomes (CLs) are
superior to either neutral or anionic liposomes as gene delivery carrier, interest in the …

Liposomal n anoparticles based on steroids and isoprenoids for nonviral gene delivery

B Maiti, S Bhattacharya - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
Natural lipid molecules are an essential part of life as they constitute the membrane of cells
and organelle. In most of these cases, the hydrophobicity of natural lipids is contributed by …

Synthesis and in vitro transfection efficiency of spermine-based cationic lipids with different central core structures and lipophilic tails

N Niyomtham, N Apiratikul, K Suksen… - Bioorganic & Medicinal …, 2015 - Elsevier
Twelve spermine-based cationic lipids with four different central core structures (di (oxyethyl)
amino, di (oxyethyl) amino carboxy, 3-amino-1, 2-dioxypropyl and 2-amino-1, 3-dioxypropyl) …

Serum Compatible Spermine‐Based Cationic Lipids with Nonidentical Hydrocarbon Tails Mediate High Transfection Efficiency

C Thongbamrer, W Roobsoong, J Sattabongkot… - …, 2022 - Wiley Online Library
Cationic lipids are widely used as nonviral synthetic vectors for gene delivery as a safer
alternative to viral vectors. In this work, a library of L‐shaped spermine‐based cationic lipids …

[HTML][HTML] High-density lipoprotein-like nanoparticles with cationic cholesterol derivatives for siRNA delivery

A Ihnatsyeu-Kachan, O Sharko, A Bekish… - Biomaterials …, 2025 - Elsevier
A new approach to siRNA delivery using high-density lipoprotein-like nanoparticles (HDL
NPs) was investigated, incorporating oligoamine and cholesterol-derived cationic lipids …