The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

K Dheda, T Gumbo, G Maartens, KE Dooley… - The lancet Respiratory …, 2017 - thelancet.com
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …

Treatment outcomes among patients with multidrug-resistant tuberculosis: systematic review and meta-analysis

EW Orenstein, S Basu, NS Shah… - The Lancet infectious …, 2009 - thelancet.com
Multidrug-resistant (MDR) tuberculosis is a growing clinical and public-health concern. To
evaluate existing evidence regarding treatment regimens for MDR tuberculosis, we used a …

Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients

SD Ahuja, D Ashkin, M Avendano, R Banerjee… - 2012 - journals.plos.org
Background Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic,
expensive, and has generally poor outcomes. We undertook an individual patient data meta …

Treatment outcomes of multidrug-resistant tuberculosis: a systematic review and meta-analysis

JC Johnston, NC Shahidi, M Sadatsafavi… - PloS one, 2009 - journals.plos.org
Background Treatment outcomes for multidrug-resistant Mycobacterium Tuberculosis
(MDRTB) are generally poor compared to drug sensitive disease. We sought to estimate …

Latent tuberculosis infection–revisiting and revising concepts

P Salgame, C Geadas, L Collins, E Jones-López… - Tuberculosis, 2015 - Elsevier
Host-and pathogen-specific factors interplay with the environment in a complex fashion to
determine the outcome of infection with Mycobacterium tuberculosis (Mtb), resulting in one …

Treatment and outcomes in children with multidrug-resistant tuberculosis: a systematic review and individual patient data meta-analysis

EP Harausz, AJ Garcia-Prats, S Law, HS Schaaf… - PLoS …, 2018 - journals.plos.org
Background An estimated 32,000 children develop multidrug-resistant tuberculosis (MDR-
TB; Mycobacterium tuberculosis resistant to isoniazid and rifampin) each year. Little is …

Comprehensive treatment of extensively drug-resistant tuberculosis

CD Mitnick, SS Shin, KJ Seung, ML Rich… - … England Journal of …, 2008 - Mass Medical Soc
Background Extensively drug-resistant tuberculosis has been reported in 45 countries,
including countries with limited resources and a high burden of tuberculosis. We describe …

Long-term outcome and safety of prolonged bedaquiline treatment for multidrug-resistant tuberculosis

L Guglielmetti, M Jaspard, D Le Dû… - European …, 2017 - publications.ersnet.org
Bedaquiline, a recently approved drug for the treatment of multidrug-resistant tuberculosis
(MDR-TB), is recommended for a duration of 24 weeks. There are scarce data on patients …

HIV coinfection in multidrug-and extensively drug-resistant tuberculosis results in high early mortality

NR Gandhi, NS Shah, JR Andrews, V Vella… - American journal of …, 2010 - atsjournals.org
Rationale: The multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis
(TB) epidemics are rapidly expanding in South Africa. Our initial report of HIV-associated …

[引用][C] Guidelines for the programmatic management of drug resistant tuberculosis: Emergency update 2008

World Health Organization - World Health Organization, 2008