Most eukaryotic mRNAs are subject to considerable post-transcriptional modification,
including capping, splicing, and polyadenylation. The process of polyadenylation adds a …

Poly (A) tails are found at the 3′ ends of almost all eukaryotic mRNAs. They are bound by
two different poly (A) binding proteins, PABPC in the cytoplasm and PABPN1 in the nucleus …

Translation, the process of mRNA-encoded protein synthesis, requires a complex apparatus,
composed of the ribosome, tRNAs and additional protein factors, including aminoacyl tRNA …

The PABP family of proteins were originally thought of as a simple shield for the mRNA poly
(A) tail. Years of research have shown that PABPs interact not only with the poly (A) tail, but …

The C‐terminal domain of poly (A)‐binding protein (PABC) is a peptide‐binding domain
found in poly (A)‐binding proteins (PABPs) and a HECT (h omologous to E 6‐AP C‐t …

The PABP-interacting motif PAM2 has been identified in various eukaryotic proteins as an
important binding site for the PABC domain. This domain is contained in homologs of the …

The poly (A)-binding protein (PABP) is an essential protein found in all eukaryotes and is
involved in an extensive range of cellular functions, including translation, mRNA …

Viruses have evolved diverse strategies to hijack the cellular gene expression system for
their replication. The poly (A) binding proteins (PABPs), a family of critical gene expression …

MLLE (previously known as PABC) is a peptide-binding domain that is found in poly (A)-
binding protein (PABP) and EDD (E3 isolated by differential display), a HECT E3 ubiquitin …

The cytoplasmic poly (A) binding protein 1 (PABPC1) is an essential eukaryotic translational
initiation factor first described over 40 years ago. Most studies of PABPC1 have focused on …