A physiological level of oxygen/nitrogen free radicals and non-radical reactive species
(collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is …

Oxidative stress (OS), defined as disturbances in the pro-/antioxidant balance, is harmful to
cells due to the excessive generation of highly reactive oxygen (ROS) and nitrogen (RNS) …

Significance: A common link between all forms of acute and chronic kidney injuries,
regardless of species, is enhanced generation of reactive oxygen species (ROS) and …

Significance: Intrarenal oxidative stress plays a critical role in the initiation and progression
of diabetic kidney disease (DKD). Enhanced oxidative stress results from overproduction of …

Reactive oxygen species (ROS) play an important role in normal cellular physiology. They
regulate different biologic processes such as cell defense, hormone synthesis and signaling …

Significance: Chronic kidney disease (CKD) can be regarded as a burden of lifestyle
disease that shares common underpinning features and risk factors with the aging process; …

Progression of fibrosis involves interstitial hypercellularity, matrix accumulation, and atrophy
of epithelial structures, resulting in loss of normal function and ultimately organ failure. There …

Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular
and cellular dysfunction that plays a major role in ageing and most age-related and …

Significance: Renal oxidative stress can be a cause, a consequence, or more often a
potentiating factor for hypertension. Increased reactive oxygen species (ROS) in the kidney …

Epidemiological studies have provided the evidence for association between nephrolithiasis
and a number of cardiovascular diseases including hypertension, diabetes, chronic kidney …