Immunobiology and pathogenesis of viral hepatitis

LG Guidotti, FV Chisari - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Among the many viruses that are known to infect the human liver, hepatitis B virus (HBV)
and hepatitis C virus (HCV) are unique because of their prodigious capacity to cause …

Noncytolytic control of viral infections by the innate and adaptive immuneresponse

LG Guidotti, FV Chisari - Annual review of immunology, 2001 - annualreviews.org
This review describes the contribution of noncytolytic mechanisms to the control of viral
infections with a particular emphasis on the role of cytokines in these processes. It has long …

Beneficial actions of melatonin in the management of viral infections: a new use for this “molecular handyman”?

JA Boga, A Coto‐Montes… - Reviews in medical …, 2012 - Wiley Online Library
SUMMARY Melatonin (N‐acetyl‐5‐methoxytryptamine) is a multifunctional signaling
molecule that has a variety of important functions. Numerous clinical trials have examined …

Deciphering the potential of baicalin as an antiviral agent for Chikungunya virus infection

A Oo, K Rausalu, A Merits, S Higgs, D Vanlandingham… - Antiviral research, 2018 - Elsevier
The past decade has seen the re-emergence of Chikungunya virus (CHIKV) as a major
global health threat, affecting millions around the world. Although fatal infections are rare …

[HTML][HTML] Physiological significance of apoptosis in animal virus infection

AH Koyama, T Fukumori, M Fujita, H Irie, A Adachi - Microbes and infection, 2000 - Elsevier
In contrast to insect viruses, animal viruses can produce considerable amounts of progeny
virus in cells undergoing apoptosis. Nevertheless, viruses in general have acquired the …

HBV pathogenesis in animal models: recent advances on the role of platelets

M Iannacone, G Sitia, ZM Ruggeri, LG Guidotti - Journal of hepatology, 2007 - Elsevier
Hepatitis B virus (HBV) causes acute and chronic necroinflammatory liver diseases and
hepatocellular carcinoma (HCC). HBV replicates noncytopathically in the hepatocyte, and …

Nonvirion protein of novirhabdovirus suppresses apoptosis at the early stage of virus infection

A Ammayappan, VN Vakharia - Journal of virology, 2011 - Am Soc Microbiol
Viral hemorrhagic septicemia virus (VHSV) and infectious hematopoietic necrosis virus
(IHNV) are members of the genus Novirhabdovirus within the Rhabdoviridae family, which …

[HTML][HTML] Loss of function of the influenza A virus NS1 protein promotes apoptosis but this is not due to a failure to activate phosphatidylinositol 3-kinase (PI3K)

D Jackson, MJ Killip, CS Galloway, RJ Russell… - Virology, 2010 - Elsevier
A panel of influenza A viruses encoding mutant NS1 proteins was created in which a
number of NS1 functions, including interactions with dsRNA, PI3K, CPSF30 and PKR, were …

Physiological significance of apoptosis during animal virus infection

AH Koyama, A Adachi, H Irie - International reviews of immunology, 2003 - Taylor & Francis
Apoptosis has been considered to be a host defense mechanism against viral infection in
multicellular organisms. This is based on the findings that apoptogenic mutants of insect …

[HTML][HTML] Lithium inhibits NF-κB nuclear translocation and modulate inflammation profiles in Rift valley fever virus-infected Raw 264.7 macrophages

RT Makola, J Kgaladi, GK More, P Jansen van Vuren… - Virology journal, 2021 - Springer
Abstract Introduction Rift Valley fever virus (RVFV) is a zoonotic life-threatening viral
infection endemic across sub-Saharan African countries and the Arabian Peninsula; …