5-Aminolevulinic acid (5-ALA) is the key precursor for the biosynthesis of tetrapyrrole
compounds, with wide applications in medicine, agriculture and other burgeoning fields …

Background Intramedullary spinal cord tumors (IMSCTs) are rare neoplasms and their
management involves tumors resection in most cases. Regarding the surgical procedure …

Intraoperative fluorescence-based tumor imaging plays a crucial role in performing the
oncological safe tumor resection with the advantage of differentiating tumor from normal …

Objective Peripheral nerve sheath tumors (PNST) include mainly schwannomas and
neurofibromas. Surgical resection represents the mainstay of treatment but due to their …

OBJECTIVE Benign peripheral nerve sheath tumors (PNSTs) include mainly schwannomas—
the most common tumors arising from peripheral nerves—and neurofibromas. Due to their …

Technological innovations in spinal intradural tumor surgery simplify treatment. Surgical
treatment of cranial benign and malignant pathologies under microscope with sodium (Na) …

Spinal intradural tumors are rare lesions accounting for less than 15% of central nervous
system neoplasms. They are categorized as intramedullary and extramedullary according to …

Background: 5-aminolevulinic acid (5-ALA) use is well established in the resection of adult
high-grade gliomas. There is growing interest in its usefulness in the paediatric population …

The spinal cord occupies a narrow region, which is tightly surrounded by vertebrae as well
as ligaments, and spinal tumors can damage this structure and deprive patients of their …

Abstract Background 5-Aminolevulinic acid (5-ALA) is a naturally occurring metabolic
precursor of heme, and 5-ALA combined with ferrous iron can induce heme oxygenase-1 …