Anatomical, histomorphological and molecular classification of cholangiocarcinoma
Cholangiocarcinoma constitutes a heterogeneous group of malignancies that can emerge at
any point of the biliary tree. Cholangiocarcinoma is classified into intrahepatic, perihilar and …
any point of the biliary tree. Cholangiocarcinoma is classified into intrahepatic, perihilar and …
Roles and mechanisms of BAP1 deubiquitinase in tumor suppression
The BAP1 gene has emerged as a major tumor suppressor mutated with various
frequencies in numerous human malignancies, including uveal melanoma, malignant …
frequencies in numerous human malignancies, including uveal melanoma, malignant …
Probing the tumor suppressor function of BAP1 in CRISPR-engineered human liver organoids
The deubiquitinating enzyme BAP1 is a tumor suppressor, among others involved in
cholangiocarcinoma. BAP1 has many proposed molecular targets, while its Drosophila …
cholangiocarcinoma. BAP1 has many proposed molecular targets, while its Drosophila …
Treatment of Intrahepatic Cholangiocarcinoma—a multidisciplinary approach
F Krenzien, N Nevermann, A Krombholz, C Benzing… - Cancers, 2022 - mdpi.com
Simple Summary This review discusses multimodality treatment strategies for intrahepatic
cholangiocarcinoma (iCC). Surgical resection remains the only potentially curative …
cholangiocarcinoma (iCC). Surgical resection remains the only potentially curative …
Biliary tract cancer: state of the art and potential role of DNA damage repair
A Lamarca, J Barriuso, MG McNamara… - Cancer Treatment …, 2018 - Elsevier
Biliary tract cancers (BTCs), including cholangiocarcinoma, gallbladder cancer and
ampullary cancers, are poor-prognosis malignancies. Most patients are diagnosed with …
ampullary cancers, are poor-prognosis malignancies. Most patients are diagnosed with …
The tumor suppressor BAP1 regulates the Hippo pathway in pancreatic ductal adenocarcinoma
HJ Lee, T Pham, MT Chang, D Barnes, AG Cai… - Cancer research, 2020 - AACR
The deubiquitinating enzyme BAP1 is mutated in a hereditary cancer syndrome with a high
risk for mesothelioma and melanocytic tumors. Here, we show that pancreatic intraepithelial …
risk for mesothelioma and melanocytic tumors. Here, we show that pancreatic intraepithelial …
CD117, BAP1, MTAP, and TdT is a useful immunohistochemical panel to distinguish thymoma from thymic carcinoma
M Angirekula, SY Chang, SM Jenkins, PT Greipp… - Cancers, 2022 - mdpi.com
Simple Summary Thymic epithelial tumors, including thymomas and thymic carcinomas are
malignant neoplasms that occur in the prevascular (anterior) mediastinum. Thymic …
malignant neoplasms that occur in the prevascular (anterior) mediastinum. Thymic …
[HTML][HTML] The advancement of long non-coding RNAs in cholangiocarcinoma development
F Jiang, X Ling - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Cholangiocarcinoma (CCA) is a malignancy with increasing incidence in recent years. CCA
patients are usually diagnosed at advanced stage due to lack of apparent symptoms and …
patients are usually diagnosed at advanced stage due to lack of apparent symptoms and …
[HTML][HTML] Exposure to asbestos and increased intrahepatic cholangiocarcinoma risk: growing evidences of a putative causal link
To date the true global incidence of intrahepatic cholangiocarcinoma (iCCA) and the
underlying risk factors remain to be fully defined, in particular, the role of occupational and …
underlying risk factors remain to be fully defined, in particular, the role of occupational and …