Enzyme-mimicking capacities of carbon-dots nanozymes: Properties, catalytic mechanism, and applications–A review

DO Lopez-Cantu, RB González-González… - International Journal of …, 2022 - Elsevier
Nanozymes, novel engineered nanomaterial-based artificial enzymes, have been
developed to overcome intrinsic drawbacks exist in natural enzymes including high-cost …

Virulence factors of the Mycobacterium tuberculosis complex

MA Forrellad, LI Klepp, A Gioffré, J Sabio y Garcia… - Virulence, 2013 - Taylor & Francis
The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …

Catalysis and Electron Transfer in De Novo Designed Metalloproteins

KJ Koebke, TBJ Pinter, WC Pitts, VL Pecoraro - Chemical reviews, 2022 - ACS Publications
One of the hallmark advances in our understanding of metalloprotein function is showcased
in our ability to design new, non-native, catalytically active protein scaffolds. This review …

[HTML][HTML] Activation of superoxide dismutases: putting the metal to the pedal

VC Culotta, M Yang, TV O'Halloran - Biochimica et Biophysica Acta (BBA) …, 2006 - Elsevier
Superoxide dismutases (SOD) are important anti-oxidant enzymes that guard against
superoxide toxicity. Various SOD enzymes have been characterized that employ either a …

Mycobacterium tuberculosis and the intimate discourse of a chronic infection

DG Russell - Immunological reviews, 2011 - Wiley Online Library
Mycobacterium tuberculosis is an extremely successful pathogen that demonstrates the
capacity to modulate its host both at the cellular and tissue levels. At the cellular level, the …

An electron transfer path connects subunits of a mycobacterial respiratory supercomplex

H Gong, J Li, A Xu, Y Tang, W Ji, R Gao, S Wang, L Yu… - Science, 2018 - science.org
INTRODUCTION Cellular respiration is a core feature in the metabolism of many organisms
that allows for the generation of a proton gradient across a membrane. During respiration …

Elemental economy: microbial strategies for optimizing growth in the face of nutrient limitation

SS Merchant, JD Helmann - Advances in microbial physiology, 2012 - Elsevier
Microorganisms play a dominant role in the biogeochemical cycling of nutrients. They are
rightly praised for their facility for fixing both carbon and nitrogen into organic matter, and …

Design and evolution of chimeric streptavidin for protein-enabled dual gold catalysis

F Christoffel, NV Igareta, MM Pellizzoni… - Nature Catalysis, 2021 - nature.com
Artificial metalloenzymes result from anchoring an organometallic catalyst within an
evolvable protein scaffold. Thanks to its dimer of dimers quaternary structure, streptavidin …

Bacillus Calmette-Guérin strain differences have an impact on clinical outcome in bladder cancer immunotherapy

CA Rentsch, FD Birkhäuser, C Biot, JR Gsponer… - European urology, 2014 - Elsevier
Background Whether the commonly used bacillus Calmette-Guérin (BCG) strains
Connaught and Tice confer different treatment responses in non–muscle-invasive bladder …

CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator

T Liu, A Ramesh, Z Ma, SK Ward, L Zhang… - Nature chemical …, 2007 - nature.com
Copper is an essential element that becomes highly cytotoxic when concentrations exceed
the capacity of cells to sequester the ion. Here, we identify a new copper-specific repressor …