Compulsive behaviors are driven by repetitive urges and typically involve the experience of
limited voluntary control over these urges, a diminished ability to delay or inhibit these …

Tissue engineering and regenerative medicine (TERM) are paving the way to the generation
of functional and mature biological tissues that closely emulate cellular, biochemical, and …

Electrical stimulation is an effective tool for mapping and altering brain connectivity, with
applications ranging from treating pharmacology-resistant neurological disorders to …

Striatal cholinergic interneurons (ChIs) are central for the processing and reinforcement of
reward‐related behaviors that are negatively affected in states of altered dopamine …

A growing body of evidence suggests that nucleus accumbens (NAc) plays a significant role
not only in the physiological processes associated with reward and satisfaction but also in …

Nicotine addiction is highly prevalent in current society and is often comorbid with other
diseases. In the central nervous system, nicotine acts as an agonist for nicotinic …

Background Deep brain stimulation is an established therapy for several neurological
disorders; however, its effects on neuronal activity vary across brain regions and depend on …

Neuro-stimulation techniques have gradually evolved over the decades and have emerged
potential therapeutic modalities for the treatment of psychiatric disorders, especially …

Clinical outcome of deep brain stimulation (DBS) for obsessive-compulsive disorder (OCD)
shows robust effects in terms of a mean Yale-Brown Obsessive-Compulsive Scale (YBOCS) …

Deep brain stimulation of the nucleus accumbens (NAc-DBS) is an emerging therapy for
diverse, refractory neuropsychiatric diseases. Although DBS therapy is broadly …