G El Helou, RR Razonable - Infection and drug resistance, 2019 - Taylor & Francis
Cytomegalovirus (CMV) is a leading opportunistic infection in immune compromised patients, including allogeneic hematopoietic stem cell (HSCT) or solid organ transplant …
RR Razonable, A Humar… - American journal of …, 2013 - Elsevier
Cytomegalovirus (CMV) is a ubiquitous herpes virus that infects the majority of humans (1). The seroprevalence rates of CMV ranges from 30–97%(2, 3). Primary infection manifests as …
RF Chemaly, AJ Ullmann, S Stoelben… - … England Journal of …, 2014 - Mass Medical Soc
Background Cytomegalovirus (CMV) infection is a leading cause of illness and death in patients who have undergone allogeneic hematopoietic-cell transplantation. Available …
K Chen, MP Cheng, SP Hammond, H Einsele… - Blood …, 2018 - ashpublications.org
Patients treated with allogeneic hematopoietic cell transplantation (HCT) are at risk of cytomegalovirus (CMV) reactivation and disease, which results in increased morbidity and …
G Ligat, R Cazal, S Hantz, S Alain - FEMS microbiology reviews, 2018 - academic.oup.com
Human cytomegalovirus (HCMV) is responsible for life-threatening infections in immunocompromised individuals and can cause serious congenital malformations …
The recent approval of letermovir marks a new era of therapy for human cytomegalovirus (HCMV) infections, particularly for the prevention of HCMV disease in hematopoietic stem …
N Turner, A Strand, DS Grewal, G Cox… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Treatment options for drug-resistant cytomegalovirus (CMV) are limited. Letermovir is a novel antiviral recently approved for CMV prophylaxis following hematopoietic cell …
S Stoelben, W Arns, L Renders, J Hummel… - Transplant …, 2014 - Wiley Online Library
Cytomegalovirus (CMV) infection remains a significant cause of morbidity and mortality in transplant recipients. Letermovir (AIC 246), is a novel anti‐HCMV drug in development …
The prevention and treatment of human cytomegalovirus (HCMV) infections is based on the use of antiviral agents that currently target the viral DNA polymerase and that may cause …