Molecular signaling regulating endometrium–blastocyst crosstalk

M Massimiani, V Lacconi, F La Civita, C Ticconi… - International journal of …, 2019 - mdpi.com
Implantation of the embryo into the uterine endometrium is one of the most finely-regulated
processes that leads to the establishment of a successful pregnancy. A plethora of factors …

Expression and function of the epidermal growth factor receptor in physiology and disease

J Chen, F Zeng, SJ Forrester, S Eguchi… - Physiological …, 2016 - journals.physiology.org
The epidermal growth factor receptor (EGFR) is the prototypical member of a family of
membrane-associated intrinsic tyrosine kinase receptors, the ErbB family. EGFR is activated …

Young LINE-1 transposon 5′ UTRs marked by elongation factor ELL3 function as enhancers to regulate naïve pluripotency in embryonic stem cells

S Meng, X Liu, S Zhu, P Xie, H Fang, Q Pan, K Fang… - Nature cell …, 2023 - nature.com
LINE-1s are the major clade of retrotransposons with autonomous retrotransposition activity.
Despite the potential genotoxicity, LINE-1s are highly activated in early embryos. Here we …

Human endometrial exosomes contain hormone-specific cargo modulating trophoblast adhesive capacity: insights into endometrial-embryo interactions

DW Greening, HPT Nguyen, K Elgass… - Biology of …, 2016 - academic.oup.com
Embryo implantation into receptive endometrium requires synergistic endometrial-blastocyst
interactions within the uterine cavity and is essential for establishing pregnancy. We …

Maternal tract factors contribute to paternal seminal fluid impact on metabolic phenotype in offspring

JJ Bromfield, JE Schjenken, PY Chin… - Proceedings of the …, 2014 - National Acad Sciences
Paternal characteristics and exposures influence physiology and disease risks in progeny,
but the mechanisms are mostly unknown. Seminal fluid, which affects female reproductive …

Uterine glands: developmental biology and functional roles in pregnancy

AM Kelleher, FJ DeMayo, TE Spencer - Endocrine reviews, 2019 - academic.oup.com
All mammalian uteri contain glands in the endometrium that develop only or primarily after
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …

[PDF][PDF] Metabolism of the preimplantation embryo: 40 years on

HJ Leese - Reproduction, 2012 - scholar.archive.org
This review considers how our understanding of preimplantation embryo metabolism has
progressed since the pioneering work on this topic in the late 1960s and early 1970s …

Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension

WY Kwong, AE Wild, P Roberts, AC Willis… - …, 2000 - journals.biologists.com
Epidemiological studies have indicated that susceptibility of human adults to hypertension
and cardiovascular disease may result from intrauterine growth restriction and low birth …

Developmental biology of uterine glands

CA Gray, FF Bartol, BJ Tarleton, AA Wiley… - Biology of …, 2001 - academic.oup.com
All mammalian uteri contain endometrial glands that synthesize or transport and secrete
substances essential for survival and development of the conceptus (embryo/fetus and …

Seminal plasma and male factor signalling in the female reproductive tract

SA Robertson - Cell and tissue research, 2005 - Springer
In mammals, insemination results in the transmission of seminal factors that act, in the
female reproductive tract, to promote sperm survival, to “condition” the female immune …