Recent advances on the structure and the function relationships of the TRPV4 ion channel

R Sánchez-Hernández, M Benítez-Angeles… - Channels, 2024 - Taylor & Francis
The members of the superfamily of Transient Receptor Potential (TRP) ion channels are
physiologically important molecules that have been studied for many years and are still …

A journey from molecule to physiology and in silico tools for drug discovery targeting the transient receptor potential vanilloid type 1 (TRPV1) channel

CA Amaya-Rodriguez, K Carvajal-Zamorano… - Frontiers in …, 2024 - frontiersin.org
The heat and capsaicin receptor TRPV1 channel is widely expressed in nerve terminals of
dorsal root ganglia (DRGs) and trigeminal ganglia innervating the body and face …

Praziquantel inhibits Caenorhabditis elegans development and species-wide differences might be cct-8-dependent

J Wit, CM Dilks, G Zhang, KSK Guisbert, S Zdraljevic… - Plos one, 2023 - journals.plos.org
Anthelmintic drugs are used to treat parasitic roundworm and flatworm infections in humans
and other animals. Caenorhabditis elegans is an established model to investigate …