Various frameworks and methods, such as quality by design (QbD), real time release test
(RTRT), and continuous process verification (CPV), have been introduced to improve drug …

Nanocarriers (NCs) have shown potential in delivering hydrophobic cytotoxic drugs and
tumor-specific targeting. However, the inability to penetrate the tumor microenvironment and …

Abstract Background Quality by Design (QbD) is a pharmaceutical quality management
system that predicts, controls, and systematically responds to risks that may occur in the …

In this study, a compartmental population balance model (CPBM) is developed as a
predictive tool of particle size distribution (PSD) for wet granulation in co-rotating twin-screw …

Upstream bioprocess characterization and optimization are time and resource‐intensive
tasks. Regularly in the biopharmaceutical industry, statistical design of experiments (DoE) in …

A green, robust and fast stability indicating chromatographic method has been developed for
concomitant analysis of fluorescein sodium and benoxinate hydrochloride in the presence of …

Proper antibiotic use becomes a fundamental consideration to minimize the chance of
resistance threat. The nasal route has the potential as an appropriate way of administration …

Introduction The pharmaceutical industry is gradually changing batch-wise manufacturing
processes to continuous manufacturing processes, due to the advantages it has to offer. The …

In the present investigation, we attempted to develop a lycopene-in-β-CD-in-phospholipid
vesicles (LCPV) with the sole aim of combining the solubilizing power of β-CD with the …

Emulsion electrospinning is a multifactorial process used to generate nanofibers loaded with
hydrophilic drugs or macromolecules for diverse biomedical applications. Emulsion …