Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract disease in
young children and elderly people. Although the virus was isolated in 1955, an effective …

Membrane fusion is an essential step when enveloped viruses enter cells. Lipid bilayer
fusion requires catalysis to overcome a high kinetic barrier; viral fusion proteins are the …

Nipah virus (NiV) and Hendra virus (HeV) are highly pathogenic zoonotic henipaviruses
(HNVs) responsible for recurrent outbreaks of encephalitis and respiratory illness. As the …

Paramyxoviruses are enveloped, nonsegmented, negative-strand RNA viruses that cause a
wide spectrum of human and animal diseases. The viral genome, packaged by the …

Highlights•Most paramyxoviruses require attachment and fusion (F) proteins for cell
entry.•Competing 'clamp'and 'provocateur'models have been proposed as entry …

Measles virus (MeV), a highly contagious member of the Paramyxoviridae family, causes
measles in humans. The Paramyxoviridae family of negative single-stranded enveloped …

Highlights•Cryo-electron tomography reconstructions of paramyxovirus particles have
yielded novel insight into virion assembly and organization.•Newcastle disease virus matrix …

Research in the last decade has uncovered many new paramyxoviruses, airborne agents
that cause epidemic diseases in animals including humans. Most paramyxoviruses enter …

Summary Hendra (HeV) and Nipah (NiV) viruses are emerging zoonotic pathogens in the
Henipavirus genus causing outbreaks of disease with very high case fatality rates. Here, we …

The Paramyxoviridae include some of the great and ubiquitous disease-causing viruses of
humans and animals. In most paramyxoviruses, two viral membrane glycoproteins, fusion …