Abstract The Editors of the Journal of Alzheimer's Disease invited Professor Patrizia Mecocci
to contribute a review article focused on the importance and implications of her research on …

Since the first mitochondrial dysfunction was described in the 1960s, the medicine has
advanced in its understanding the role mitochondria play in health, disease, and aging. A …

Loss of function in mitochondria, the key organelle responsible for cellular energy
production, can result in the excess fatigue and other symptoms that are common complaints …

Is there any reason to write a third book on the topic of oxygen-ozone therapy? The first was
written four years ago for italian physicians, who, for some time, had complained about the …

The antioxidant enzyme superoxide dismutase 1 (SOD1) is a critical player of the
antioxidative defense whose activity is altered in several chronic diseases, including …

Ageing is a complex process that in muscle in usually associated with a decrease in mass,
strength, and velocity of contraction. One of the most striking effects of ageing on muscle is …

This study aims to improve the health of patients suffering from chronic fatigue syndrome
(CFS) by interventions based on the biochemistry of the illness, specifically the function of …

The aetiology of chronic fatigue syndrome (CFS) is unknown; however, recent evidence
suggests excessive free radical (FR) generation may be involved. This study investigated for …

Glutathione (GSH) has a crucial role in cellular signaling and antioxidant defenses either by
reacting directly with reactive oxygen or nitrogen species or by acting as an essential …

This book represents the first serious attempt to explain the fundamental basis of
ozonetherapy and is a relevant step towards achieving further progress. Ozone is now …