This review summarizes the trends in the formation of complex or not so complex
heterocyclic structures through 1, 3-dipolar cycloadditions of azomethine ylides. Diastereo …

Spirocompounds constitute an important class of organic frameworks enveloping numerous
pharmacological activities, among them, the promising anticancer potential of …

Novel fluoroquinolone–pyrazine conjugates 7a–h with amino acid linkers were synthesized
in good yields utilizing benzotriazole chemistry. Antimicrobial bioassay showed that the …

Click chemistry technique led to novel 1, 2, 3-triazole-quinine conjugates 8a–g, 10a–o, 11a–
h and 13 utilizing benzotriazole-mediated synthetic approach with excellent yields. Some of …

Alzheimer's disease is a neurodegenerative disorder that impacts memory, thinking, and
behavior, and currently, there is no effective cure available for its treatment. This study …

In an attempt to develop novel α-amylase inhibitors, a series of 2, 4-thiazolidinedione fused
spiropyrrolidine-oxindole and 1, 2, 3-triazole scaffolds were designed, synthesized via a …

The broad spectrum of curcumin's beneficial properties has encouraged medicinal
researchers to investigate its therapeutic efficacy against diverse diseases. The clinical …

Cancer is one of the most significant health challenges worldwide. Various techniques, tools
and therapeutics/materials have been developed in the last few decades for the treatment of …

A facile synthesis of novel dispiroheterocycles has been developed through one-pot [3+ 2]
cycloaddition between isatins, amino acids, and aurones. Thirty different dispiroheterocycles …

3, 4-Diaryl-11-methyl-7-[(aryl) methylidene]-4, 5, 11-triazatricyclo [6.2. 1.0* 2, 6*] undec-5-
enes 14a–s were synthesized through reaction of 2, 4-bis [(aryl) methylidene]-8-methyl-8 …