Members of the family of B9 vitamins are commonly known as folates. They are derived
entirely from dietary sources and are key one-carbon donors required for de novo nucleotide …

This review attempts to provide a comprehensive overview of the biology of the
physiologically and pharmacologically important transport system termed the “reduced folate …

During the fifteen years since the bestselling first edition of Folate in Health and Disease
was published, there have been thousands of new research studies related to folate and its …

Drug‐induced gingival overgrowth (DIGO) is a disfiguring side effect of anti‐convulsants,
calcineurin inhibitors, and calcium channel blocking agents. A unifying hypothesis has been …

Folates are members of the B‐class of vitamins, which are required for the synthesis of
purines and pyrimidines, and for the methylation of essential biological substances …

Membrane transport of folates is essential for the survival of all mammalian cells and
transport of antifolates is an important determinant of antifolate activity. While a major focus …

Background: Folic aid plays an essential role in cellular metabolism. Its deficiency can lead
to neural tube defects. However, optimization of body folate homeostasis can reduce the …

The major short-chain fatty acid (SCFA) butyrate is produced in the colonic lumen by
bacterial fermentation of dietary fiber. Butyrate serves as primary fuel for the colonocytes and …

Folates are essential for life and folate deficiency contributes to a host of health problems
including cardiovascular disease, fetal abnormalities, neurological disorders, and cancer …

Haem carrier protein 1 (HCP1) was originally identified and characterised as a mammalian
haem transporter. However, recent evidence has shown that it is also a proton-coupled …