Methods and compositions for nucleic acid analysis

S Saxonov - US Patent 9,347,059, 2016 - Google Patents
Provided herein are methods, compositions, and kits for assays, many of which involve
amplification reactions such as digital PCR or droplet digital PCR. The assays may be used …

Compositions and methods for molecular labeling

M Samuels, JC Olson, A Watson, K Brown… - US Patent …, 2015 - Google Patents
2012-05-08 Assigned to RAINDANCE TECHNOLOGIES, INC. reassignment RAINDANCE
TECHNOLOGIES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Droplet-based assay system

BW Colston, BJ Hindson, KD Ness… - US Patent …, 2015 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
42311957&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Microfluidic devices and methods of use thereof

D Link, M Weiner, D Marran… - US Patent App. 11/803,101, 2008 - Google Patents
2007-07-31 Assigned to RAINDANCE TECHNOLOGIES, INC. reassignment RAINDANCE
TECHNOLOGIES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Microfluidic devices

D Link, M Weiner, D Marran… - US Patent App. 11/803,104, 2008 - Google Patents
The present invention provides novel microfluidic substrates and methods that are useful for
performing biological, chemical and diagnostic assays. The substrates can include a …

Method and apparatus for fluid dispersion

HA Stone, SL Anna, N Bontoux, DR Link… - US Patent …, 2010 - Google Patents
US7708949B2 - Method and apparatus for fluid dispersion - Google Patents US7708949B2
- Method and apparatus for fluid dispersion - Google Patents Method and apparatus for fluid …

Fluorocarbon emulsion stabilizing surfactants

C Holtze, DA Weitz, JB Hutchison - US Patent 9,012,390, 2015 - Google Patents
Surfactants (eg, fluorosurfactants) for stabilizing aqueous or hydrocarbon droplets in a
fluorophilic continuous phase are presented. In some embodiments, fluorosurfactants …

Sample multiplexing

D Link - US Patent 8,841,071, 2014 - Google Patents
The invention generally relates to methods for sample multiplexing. In certain embodiments,
methods of the invention obtaining a plurality of different reactant molecules, attaching a …

Droplet generation for droplet-based assays

KD Ness, CF Kelly, DA Masquelier - US Patent 9,500,664, 2016 - Google Patents
A system, including method and apparatus, for generating droplets suitable for droplet-
based assays. The disclosed systems may include either one-piece or multi-piece droplet …

Microfluidic Devices and Methods of Use in The Formation and Control of Nanoreactors

DR Link, L Boitard, J Branciforte, Y Charles… - US Patent App. 12 …, 2010 - Google Patents
BACKGROUND 0002 High throughput molecular screening (HTS) is the automated, rapid
testing of thousands of distinct Small mol ecules or probes in cellular models of biological …