Skin aging is one of the most evident signs of human aging. Modification of the skin during
the life span is characterized by fine lines and wrinkling, loss of elasticity and volume, laxity …

Most cancers arise in individuals over the age of 60. As the world population is living longer
and reaching older ages, cancer is becoming a substantial public health problem. It is …

Lipid vesicles can provide a cost-effective enhancement of skin drug absorption when
vesicle production process is optimised. It is an important challenge to design the ideal …

In this opinion, we highlight agent-based modeling as a key tool for exploration of cell–cell
and cell–environment interactions that drive cancer progression, therapeutic resistance, and …

Chronic inflammation is a prerequisite for the development of cancers. Here, we present the
framework of a novel theory termed as Cancer Evolution-Development (Cancer Evo-Dev) …

Although senescence was originally described as an in vitro acquired cellular characteristic,
it was recently recognized that senescence is physiologically and pathologically involved in …

The Hybrid Automata Library (HAL) is a Java Library developed for use in mathematical
oncology modeling. It is made of simple, efficient, generic components that can be used to …

To study cutaneous pigmentation in a physiological context, we have previously developed
a functional pigmented reconstructed skin model composed of a melanocyte-containing …

Cellular senescence is now recognized as one of the nine hallmarks of ageing. Recent data
show the involvement of senescent cells in tissue ageing and some age-related diseases …

Epithelial to mesenchymal transition (EMT), the process during which epithelial cells lose
adhesions with neighbouring cells and get converted to migratory and invasive cells, is …