Retinitis pigmentosa (RP) is an inherited condition that features degeneration of rod and
cone photoreceptors. In all forms of RP, the genetic mutation is expressed exclusively in …

Trophic factors are endogenously secreted proteins that act in an autocrine and/or paracrine
fashion to affect vital cellular processes such as proliferation, differentiation, and …

Progressive photoreceptor degeneration resulting from genetic and other factors is a leading
and largely untreatable cause of blindness worldwide. The object of this study was to find a …

Background Retinitis pigmentosa belongs to a large group of degenerative diseases of the
retina with a hereditary background. It involves loss of retinal photoreceptor cells and …

Stem cells derived from the human brain and grown as neurospheres (HuCNS‐SC) have
been shown to be effective in treating central neurodegenerative conditions in a variety of …

The aim of retinal transplantation is to prevent blindness and to restore eyesight, ie to rescue
photoreceptors or to replace damaged photoreceptors with the hope of re-establishing …

In this review we examine the potential of embryonic stem cells (ESCs) for use in the
treatment of retinal diseases involving photoreceptors and retinal pigment epithelium (RPE) …

Retinal degeneration is an irreversible phenomenon caused by various disease conditions
including age‐related macular degeneration (AMD) and retinitis pigmentosa (RP). During …

Cisplatin (CDDP), a major chemotherapeutic agent used to treat solid tumors, is known to
induce acute renal failure (ARF). The progression of tissue injury involves the coordination …

To examine how rod and cone function are differentially affected during retinal
degeneration, and after subretinal cell grafting, we obtained light-and dark-adaptation …