In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

Chorioamnionitis is a common complication of pregnancy associated with significant
maternal, perinatal, and long-term adverse outcomes. Adverse maternal outcomes include …

Preterm babies are prone to serious illness or death during the neonatal period. Without
appropriate treatment, those who survive are at increased risk of lifelong disability and poor …

Background Progesterone administration has been shown to reduce the risk of preterm birth
and neonatal morbidity in women at high risk, but there is uncertainty about longer term …

Despite substantial progress in prevention of perinatal group B streptococcal (GBS) disease
since the 1990s, GBS remains the leading cause of early-onset neonatal sepsis in the …

Background Despite decades of attempts to link infectious agents to preterm birth, an exact
causative microbe or community of microbes remains elusive. Nonculture 16S ribosomal …

Although individual behaviors have not been proven to have a strong influence on the risk of
preterm birth, consistent evidence suggests that a constellation of favorable lifestyle factors …

Objective The purpose of this study was to compare intraamniotic inflammation vs microbial
invasion of the amniotic cavity (MIAC) as predictors of adverse outcome in preterm labor with …

BACKGROUND The use of antenatal steroid therapy is common in pregnancy. In early
pregnancy, steroids may be used in women for the treatment of recurrent miscarriage or fetal …

Group B streptococcus (GBS) remains a leading cause of serious neonatal infection despite
great progress in perinatal GBS disease prevention in the 1990s. In 1996, CDC, in …